OBJECTIVES Nasal septal deviation is a frequent cause of increased nasal airway resistance. A narrow nasal airway would result in a decreased airflow into the lungs. The aim of the present study was to evaluate the alterations of the pulmonary functions following septoplasty using spirometry and 6 minutes walking test (6mWT). And reveal the correlation of symptom score improvement with nasal ob...

OBJECTIVE The role of Dicer in the prognosis of cancer patients remains controversial. This systematic review is attempted to assess the influence of Dicer as a prognostic predictor for survival in diverse types of cancers. METHODS Studies were selected as candidates if they published an independent evaluation of Dicer expression level together with the correlation with prognosis in cancers. ...

BACKGROUND Randomized Controlled Trials (RCTs) represent the most valuable study design to evaluate the effectiveness of therapeutic interventions. However, flaws in design, conduct, analysis, and reporting of RCTs can cause the effect of an intervention to be under- or overestimated. These biased RCTs may be included in literature reviews. To make the assessment of Risk of Bias (RoB) consisten...

the peak age of onset of inflammatory bowel disease (ibd) is simultaneous with the peak reproductive years. patients have many concerns about the impact of ibd on fertility and pregnancy outcomes. the most important reason for voluntary childlessness is the fear of side effects from medications for ibd. decision making for medical therapy is a complex equation. it is important to summarize avai...

inflammatory bowel disease (ibd) is the term used for a group of diseases with yet unknown etiology, prevalence of which is increasing almost everywhere in the world. the disease was almost non-existent four decades ago in the east, including the middle-east, while now a days it is seen more and more. in addition to the increasing prevalence, our knowledge about its pathogenesis, clinical cours...

background: besides medical therapy, surgical interventions plays an important role in the treatment of inflammatory bowel disease (ibd), but they also involve complications and advantages. this study was undertaken to determine the characteristics and outcome of surgery in patients with ibd. â  methods: all the files of the patients admitted in nemazee and faghihi hospitals with the final diag...

abo blood type antigens are polymorphic, inherited structures presented on the surface of red blood cells. although abo blood group antigens is the most important antigens in transfusion medicine, its main role is not clearly clarified. correlation between abo blood group and susceptibility to certain infectious and non-infectious diseases is a controversial issue. since, lack of blood type ant...

ulcerative colitis and crohn's disease are chronic, relapsing, inflammatory conditions defined by their phenotypic features. family studies have identified a clear genetic influence on disease susceptibility and expression. molecular studies have identified specific genes that predispose individuals to the development of inflammatory bowel disease. some of these genes are specific to either ulc...

psychological problems play a critical role in development of cardiovascular disease. several mechanisms were suggested to explain the association and mechanism of this effect, recently. knowledge of the mechanisms mediating the association between psychological status and heart disease could help in developing treatments. the effects of mind and mood on the cardiovascular system can be due to ...