نتایج جستجو برای: opioid substance
تعداد نتایج: 236027 فیلتر نتایج به سال:
Antidepressants are commonly used in substance abusers due to the potential effect on some underlying mechanisms involved in drug use disorders and to treat comorbid depression. A systematic review of the literature of the efficacy of antidepressant drugs in subjects with drug abuse disorders, including alcohol, cocaine, nicotine and opioid, with and without comorbid depression was performed. O...
The present work aimed to investigate the effects of acute sucrose treatment on the perception of painful stimuli. Specifically, we sought to determine the involvement of the endogenous opioid peptide-mediated system as well as the role of the μ(1)-opioid receptor in antinociception organisation induced by acute sucrose intake. Nociception was assessed with the tail-flick test in rats (75, 150 ...
Abstract The aim of this research was to examine the effectiveness of supportive-expressive therapy in improving the maintenance treatment outcome for opioid dependency. For this purpose, a single case experimental design across subjects was used in which four opioid dependent subjects were assessed during baseline, intervention and follow-up phases. The assessment measures included Structured...
OBJECTIVE To provide clinicians with a brief screening tool to predict accurately which individuals may develop aberrant behaviors when prescribed opioids for chronic pain. DESIGN One hundred and eighty-five consecutive new patients treated in one pain clinic took the self-administered Opioid Risk Tool (ORT). The ORT measured the following risk factors associated in scientific literature with...
Background and Aim: The objective of this study was to determine factors associated with time to relapse and, thus, retention time, of a cohort of opioid-dependents under methadone maintenance treatment, using survival models, in the Iranian National Center for Addiction Studies (INCAS). Materials and Methods: A total of 198 opioid-dependent clients participating in the Methadone Maintenanc...
OBJECTIVE To investigate morbidity related to misuse of over-the-counter (OTC) codeine-ibuprofen analgesics. DESIGN AND SETTING Prospective case series collected from Victorian hospital-based addiction medicine specialists between May 2005 and December 2008. MAIN OUTCOME MEASURES Morbidity associated with codeine-ibuprofen misuse. RESULTS Twenty-seven patients with serious morbidity were ...
Introduction: Nowadays opioid abuse is one of the universal problems that in addition to men, women are also involved in it, the lack of resilience characteristic can increase the probability of using in the full of stress situations of life. On the other hand, there is a significant and positive relation between quality of life and resilience. So, that purpose of this study is investigation of...
Ingestion of placenta or amniotic fluid by rats has been shown to enhance ongoing opioid-mediated antinociception, but does not, by itself, produce antinociception. This enhancement is produced by an active substance(s) in placenta and amniotic fluid that we have termed POEF for placental opioid-enhancing factor. Previous research has shown that enhancement requires mediation by the gastrointes...
Background:Naltrexone is a competitive opioid receptor antagonist blocking the euphoric effects of exogenous opioids. When used concomitantly with opioids, naltrexone causes severe withdrawal symptoms.The main aim of the study is to determine the symptomatology and outcome of patients who consumed naltrexone in conjunction with an opioid substance. Methods:This cross-sectional study was perf...
Participants 124 opioid-dependent men, fulfilling DSM-III-R criteria, and living with a non-substance-abusing spouse or family member. Mean age of participants was 32 years. People allergic to or with contra-indications to naltrexone, requiring in-patient treatment, receiving counselling for abuse of other substances, and people receiving methadone maintenance therapy in the preceding 30 days w...
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