The American Cancer Society estimated that 39,610 new cases of rectal cancer were diagnosed in the United States in 2015. Surgery is the primary treatment for rectal cancer, with the majority of patients undergoing sphincter-preserving surgery with low anterior resection. Although low anterior resection can prevent patients from having a permanent colostomy, bowel dysfunction may occur in 60% t...

The optimal management of opioid-related side effects is hampered by a lack of comparative studies of management strategies. The prevalence of such side effects is influenced by the extent of disease, the patient's age, the presence of coexistent renal and hepatic disease, pulmonary disease, and cognitive dysfunction, a prior opioid history, use of polypharmacy, dose of opioid drug being admini...

abstract aim: to assess anti-neuronal antibodies (na) prevalence and their correlation with neurological disorders and bowel habits in celiac disease (cd) patients. background: neurological manifestations are estimated to occur in about 10% of celiac disease patients and na to central nervous system (cns) and enteric nervous system (ens) are found in a significant proportion of them. little is ...

In order to evaluate the effect of standardized management on spinal cord injury patients with neurogenic bowel dysfunction, 50 cases of spinal cord injury patients from January 2011 to December 2013 were treated with neurogenic bowel intestinal standardized management. The effect was compared to that with routine nursing of 32 spinal cord injury patients from January 2009 to December 2010. Dat...

BACKGROUND AND PURPOSE The effects of single-nucleotide polymorphisms (SNPs) on the cognitive function of opioid-treated patients with cancer until now have not been explored, but they could potentially be related to poor functioning. This study aimed at identifying associations between SNPs of candidate genes, high opioid dose, and cognitive dysfunction. METHODS Cross-sectional multicenter s...

BACKGROUND To evaluate the clinical features and outcome of patients with progressive neurological deficits due to disc herniation who were treated surgically within 24 h. METHODS We conducted a retrospective analysis of consecutive patients who were admitted between 2004 and 2013 via the Emergency Department. Records were screened for presenting symptoms, neurological status at admission, di...

external exposed radiation may play an important role in pathogens of irritable bowel syndrome (ibs), although is thought to arise due to a combination of genetic and environmental factors. the result is dysregulated immune responses due to alteration in the gut microbiota population and the subsequent development of gut inflammation. it has recently been shown that the effect of ionizing radia...