Dear Editor, Syphilis can present in a myriad of ways. Recognition of this “great imitator”, which can be easily treated, will greatly reduce morbidity. A 46-year-old Chinese male presented with intense inflammatory polyarthritis of his bilateral metacarpophalangeal, wrists, elbows, knees, ankles and metatarsophalangeal joints for 2 weeks. Joint tenderness was alleviated with movement and assoc...

OBJECTIVE Our purpose was to estimate and compare the cost-effectiveness of the most commonly used diagnostic tests for onychomycosis: potassium hydroxide preparation (KOH), interpreted both by a dermatologist (KOH-CLINIC) and a laboratory technician (KOH-LAB); KOH with dimethyl sulfoxide (KOH-DMSO) and with chlorazol black E (KOH-CBE), interpreted by a dermatologist; culture using dermatophyte...

Symmetrical lupoid onychodystrophy (SLO) is an immune-mediated disease in dogs affecting the claws with a suggested autoimmune aethiology. Sequence-based genotyping of the polymorphic exon 2 from DLA-DRB1, -DQA1, and -DQB1 class II loci were performed in a total of 98 SLO Gordon setter cases and 98 healthy controls. A risk haplotype (DRB1*01801/DQA1*00101/DQB1*00802) was present in 53% of cases...

1. Ruíz-Cendoya M, Madrid H, Pastor FJ, Mayayo E, Mariné M, Guarro J. Development of murine models of disseminated infection by Neoscytalidium dimidiatum. Med Mycol. 2010;48: 681--6. 2. Downs AM, Lear JT, Archer CB. Scytalidium hyalinum onychomycosis successfully treated with 5% amorolfine nail lacquer. Br J Dermatol. 1999;140:555. 3. Dunand J, Viguie C, Paugam A. Intermittent posaconazole regi...

A healthy 2-year-old girl was referred for toenail thickening and yellow discoloration; she was otherwise asymptomatic. The patient had no history of diabetes, infection, or trauma to her toenails. Physical examination revealed both great toenails to have marked thickening of the nail plate with closely spaced transverse superficial ridging, lack of luster, and dark tanyellowish discoloration (...

Nail patella syndrome (NPS) is an autosomal dominant disorder characterized by nail malformations, patellar apoplasia, or patellar hypoplasia. Mutations within the LMX1B gene are found in 85% of families with NPS; thus, this gene has been characterized as the causative gene of NPS. In this study, we identified a heterozygous microdeletion of the entire LMX1B gene using multiplex ligation-depend...

Objective: To evaluate the incidence of union, nonunion, deep infection and factors influencing the time of bone healing in the treatment of open tibial shaft fractures Gustilo and Anderson types I and II initially treated with a non penetrating external fixator (Pinless®) followed by an unreamed intramedullary locked nail (UTN®). Methods: It is a prospective study of 39 open tibial shaft fract...

Objectives To compare the long-term functional and radiographic outcomes of the proximal femoral nail antirotation-Asia (PFNA-II) and INTERTAN nail (IT) in the management of intertrochanteric femoral fractures (IFFs) (AO/OTA Type 31A1.1-A2.3) in elderly patients with primary osteoporosis. Methods A retrospective comparative study was performed in our institution. From January 2009 to March 2012...

Background: Nail biting (NB) is a common, but unresolved, problem in psychiatry, psychology, medicine and dentistry. It is the habit of biting one’s nails, is commonly observed in both children and young adults Materials & Methods: The study was a comparative cross‐ sectional microbiological study, conducted on the saliva samples of 40 chronic nail biting subjects in that 20 were males and 20 w...