INTRODUCTION The knowledge about the molecular biology of clear cell renal cell carcinoma (ccRCC) is evolving, and Carbonic Anhydrase type IX (CA-IX) has emerged as a potential prognostic marker in this challenging disease. However, most of the literature about CA-IX on ccRCC comes from series on metastatic cancer, with a lack of series on non-metastatic cancer. The objective is to evaluate the...

c-erbB-2 gene analysis by Southern and DNA dot blot methods was done in 66 tumor samples from patients with histolÃ3gica!!} node-negative breast cancer. The c-erbB-2 gene was amplified 2to >8-fold in 13 tumors (20%). None of 59 tumors that were examined by the Southern method showed c-erbB-2 gene rearrangement. r-erbB-2 amplification was analyzed in relation to other prognostic factors. The c-e...

OBJECTIVE To analyze the cytomorphologic findings of myxofibrosarcoma (MFS) on fine needle aspiration (FNA) and examine the differential diagnoses. STUDY DESIGN A retrospective review was undertaken of material from 22 patients with an FNA procedure of their tumor prior to resection. A tally was performed of all the features known in the literature, including myxoid matrix, spindle cells, nuc...

Nuclear recoils in crystal detectors generate radiation damage the form of defects that can be measured scientific-grade CCDs as local hot spots leakage current stimulated by temperature increases devices. In this proceeding, we use a neutron source to DAMIC-M CCDs, and using at different temperatures, demonstrate procedure for identifying experiment. This is first time individual generated fro...

Peripheral blood-derived inflammation-based markers, including C-reactive protein (CRP), neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR), and platelet-to-lymphocyte ratio (PLR) are indicators of prognosis in various malignant tumors. The present study aimed to identify the inflammation-based parameters that are most suitable for predicting outcomes in patients with brea...

INTRODUCTION Lymphangiogenesis has been reported to be important in the prognosis of several tumours. The aim of this study was to assess the correlation between lymphangiogenesis and clinicopathological prognostic parameters in patients with clear cell renal cell carcinoma. METHODS 62 patients with renal cell carcinoma were included in the study. The D2-40 antibody, assessed immunohistochemi...

The possibility of a state, which has imported fast reactor with closed fuel cycle enterprises, breaching the nuclear non-proliferation regime and secretly using acquired equipment, technologies, materials to originate weapons is discussed. It assumed that most likely development events could be an importing state combining clandestine overt scenarios: for preparatory period non-nuclear compone...

Optical spectroscopy was used to evaluate the transformation of nuclear morphology associated with intraepithelial neoplasia in an animal model of carcinogenesis. In this pilot study, we have assessed the capability of angle-resolved low-coherence interferometry (a/LCI) to monitor in situ the neoplastic progression of hamster trachea epithelial tissue. By using the depth resolution made possibl...

PURPOSE A computer-based system was designed, incorporating subjective criteria employed by pathologists in their usual microscopic observation of tissue samples and measurements of nuclear characteristics, with the purpose of automatically assessing urinary bladder tumour grade and predicting cancer recurrence. MATERIAL AND METHODS Ninety-two cases with urine bladder carcinoma were diagnosed...