In this paper a disseminated persistent Nocardia cyriacigeorgica infection in an immunocompetent patient is described. The patient's long-term treatment, as well as its implications for managing similar cases in the future, is emphasized. Presenting with high fever, multiple nodules, and ulcerative cutaneous lesions of body sites, the patient was treated with various antimicrobials. Under combi...

The producer of SO-075R1,a newanthracycline group antibiotic was identified as Nocardia brasiliensis. SO-075R1 was active against Gram-positive bacteria, but not active against Gram-negative bacteria or fungi. All tested Nocardia brasiliensis strains as well as the producer itself were resistant to SO-075R1, although four other pathogenic Nocardia, i.e. N. asteroides, N. nova, N. farcinica and ...

[1] In the article, “Central nervous system nocardiosis in Queensland: A report of 20 cases and review of the literature”, which appeared in Volume 95, Issue 46 inMedicine, the acknowledgement “Dr Chris Coulter and Dr Sushil Pandey of the QueenslandMycobacterium Reference Laboratory (Central Laboratory, Pathology Queensland, Brisbane) are thanked for their discussions on this topic and their su...

OBJECTIVE To determine the prevalence of HIV-1 infection in childbearing women in Nova Scotia. DESIGN An anonymous, unlinked seroprevalence study using "leftover" cord bloods. The study was done in 2 stages: I-Halifax Co. women delivering between February 1, 1992 and December 31, 1993; II-non-Halifax Co. women delivering between November 15, 1993 and December 15, 1994. RESULTS Of 9,115 deli...

Until 1960, 179 cases of infection with Nocardia asteroides had been described in the world literature. Seventeen cases in children were reported by 1963. The organism is a common saprophyte in nature with probably a world-wide distribution. Infection can be primary but is more common in patients with underlying malignancy, auto-immune disease or preceding tuberculosis. Sulphonamides, particula...

We describe a case of pulmonary nocardiosis due to Nocardia asiatica in an immunocompent 64-year-old-female. Wadowsky-Yee-Okuda-α-ketoglutarate (WYOα) agar, a selective media for Legionella species, was useful for the detection based on the growth-inhibition of normal oral flora and growth-promotion of Nocardia species.

Nocardia infection occurs primarily among patients with deficient cell-mediated immunity. The portal of entry in the majority of patients with Nocardia infection is pulmonary origin. Central venous catheter-associated bacteremia caused by Nocardia species is very rare, and the optimal management for these situations was indeterminate. Most patients were cured after discontinuation of central ve...

RATIONALE Nocardia species are aerobic saprophytic bacilli. Among Nocardia species, Nocardia otitidiscaviarum (N otitidiscaviarum) is rarely reported in pulmonary infection. PATIENT CONCERNS We reported a case of N otitidiscaviarum pneumonia in a cotton farmer. DIAGNOSES N otitidiscaviarum pneumonia was identified by mass spectroscopy. INTERVENTIONS Combined treatments (amikacin, imipenem...

Communications to the Editor clinical picture is similar to that produced by other organisms, such as mycobacteria, although Nocardia is also capable of inducing a granulomatous reaction in tissue. This gives rise to the possibility of making an erroneous diagnosis of tuberculosis, above all in areas such as Spain where this disease is relatively frequent. Although ceftriaxone has been shown to...

2 different strains of Nocardia were isolated from a lung mass in a post kidney-pancreas transplant patient through convex endobronchial ultrasound transbronchial needle aspiration (EBUS-TNBA). TBNA cultures (16S rRNA gene-targeted PCR sequencing) subsequently grew Nocardia beijingensis and Nocardia arthritidis.