To determine the role of NT3 in the postnatal maturation of Merkel cell (MC) sensory neurite complexes (touch domes), we examined the development of their neural and end-organ components in wild-type and transgenic mice that overexpress NT3 (NT3-OE). Touch domes are sensory complexes of the skin that contain specialized MCs innervated by slowly adapting type 1 (SA1) neurons. Touch domes are dep...

The pathogenesis of lymphocytic choriomeningitis virus infection in fetal, newborn, and young adult hamsters was studied. Infected newborn hamsters initially developed a persistent viremia and viruria with titers often in excess of 10(4.0) mean infectious doses/0.03 ml of blood or urine. After week 12 two different patterns of infection became evident. Approximately one-half of the hamsters eve...

Abstract Background : Bovine respiratory syncytial virus (BRSV) is a major problem for cattle worldwide during their first year of life. The aim the present study was to evaluate efficacy and longevity immunity live vaccine (NASYM, HIPRA) in presence maternally derived antibodies (MDA). Method Calves (36) were distributed four groups, based on MDA status treatment. They received NASYM or placeb...

A model of experimental postnatal hyperbilirubinemia in the rat has been developed utilizing the heme precursor delta-aminolevulinic acid (ALA) to produce jaundice during a selective time period after birth. This time period is defined as that between 7 d postnatally, when the initial postpartum alterations of serum bilirubin and heme metabolism in the neonate have subsided, and 21 d, when the ...

The article presents research materials on the adaptive and productive qualities of third-generation heifers Aberdeen Angus cattle in conditions "Zholdasbay-agro" farming enterprise North Kazakhstan region. object study was growth development obtained by Canadian European selection Aberdeen-Angus breed. According to results summary clinical signs, frequency antenatal hypotrophy newborn calves b...

search results show that numerous primary studies have been carried out in different parts of iran regarding prevalence of g6pd deficiency; if results of these studies are combined, a reliable estimation of prevalence of this factor will be achieved in iran. thus, present study, aimed to determine the prevalence of g6pd deficiency by combining findings of qualified primary studies using meta-an...

Abstract Purpose: Skeletal staining is a way to study the effect of many chemical or herbal substances on development of bones and cartilages in order to record the level of probable deformity.This article aimed to present a modified protocol to make all skeletal studies on laboratory animals possible. Materials and Methods: The important notes about skeletal staining were fixing by ethan...

Plasma catecholamine levels increase dramatically at birth. To determine the contribution of adrenal catecholamine secretion to the surge in catecholamines at birth and the role in newborn adaptation, we performed surgical adrenalectomy or sham operation on near-term ovine fetuses. After recovery in utero, the animals were delivered and supported by mechanical ventilation. Plasma catecholamine ...