نتایج جستجو برای: mometasone

تعداد نتایج: 433  

2011
SF Weinstein RA Nathan EO Meltzer D Gates H Nolte

Methods A 2–3-week run-in period with twice daily (BID) MF100μg, MF-200μg, or MF-400μg was performed before subject (≥12y) randomization to BID: MF/F-100/10μg, MF100μg, F-10μg, or placebo for 26weeks (n=746); MF/F-200/ 10mg, MF-200μg, F-10μg, or placebo for 26weeks (n=781); MF/F-200/10μg, MF/F-400/10μg, or MF-400μg for 12weeks (n=728 ). Assessment of asthma deterioration (ie, 20% decrease in fo...

2012
Donald P Tashkin Dennis E Doherty Edward Kerwin Carlos E Matiz-Bueno Barbara Knorr Tulin Shekar Davis Gates Heribert Staudinger

BACKGROUND The clinical efficacy and safety of a mometasone furoate/formoterol fumarate (MF/F) fixed-dose combination formulation administered via a metered-dose inhaler was investigated in patients with moderate to very severe chronic obstructive pulmonary disease (COPD). METHODS Two 52-week, multicenter, double-blind, placebo-controlled trials with identical study designs were conducted in ...

Journal: :Respiratory Research 2004
Anagnostis Valotis Petra Högger

Mometasone furoate (MF) is a highly potent glucocorticoid used topically to treat inflammation in the lung, nose and on the skin. However, so far no information has been published on the human glucocorticoid receptor activity of the metabolites or degradation products of MF. We have now determined the relative receptor binding affinities of the known metabolite 6beta-OH MF and the degradation p...

Journal: :Nihon Bika Gakkai Kaishi (Japanese Journal of Rhinology) 2017

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