نتایج جستجو برای: mir seid ali
تعداد نتایج: 54698 فیلتر نتایج به سال:
دریاچه مهارلو یکی از دریاچه های شور ایران است که در استان فارس و در 23 کیلومتری جنوب شرقی شیراز قرار دارد و به دلیل فاصله کم آن از شهر شیراز و مجاورت آن با تعداد زیادی روستا و نیز به دلیل استفاده از نمک دریاچه در صنایع مختلف دارای اهمیت ویژه ای است. با بکارگیری فنون سنجش از دور چند طیفی می-توان درمدت زمانی کوتاه و با کمترین هزینه و نیروی کار به اطلاعات مفیدی در زمینه زمین شیمی دریاچه ها به ویژه...
Circulating microRNAs in Early Breast Cancer Patients and Its Association With Lymph Node Metastases
MicroRNAs have emerged as important regulators of the metastatic process. In addition, circulating miRNAs appear to be surprisingly stable in peripheral blood making them ideal noninvasive biomarkers for disease diagnosis. Here, we performed a proof-of-principle study investigate expression profile and their association with lymph node status early breast cancer patients. Sentinel was detected ...
The Ras homolog (Rho) family of small GTPases comprise several proteins with prominent roles in regulation cell cycle transition, migration, and remodeling actin cytoskeleton. Expression these is regulated by factors among them are long non-coding RNAs (lncRNAs). impact lncRNAs on Rho signaling can be exerted through direct modulation expression or influencing miRNAs that negatively regulate GT...
سلول های بنیادی مشتق شده از بافت چربی انسانی (hadsc) کاندیدای مورد توجه ای در سلول درمانی بیماری های کبدی اند که تمایل ویژه ای در بدست آوردن خصوصیات کبدی به همراه پتانسیل تکثیر بالاتر و دوره کشت طولانی تر نسبت به دیگر سلول های مزانشیمی حاصل از منابع دیگر دارند. میکروrna ها (mirna ها) دسته ای از rna های غیر کد کننده هستند که به عنوان تنظیم کننده های کلیدی در فعالیت های بیولوژیکی مختلف مانند تکثی...
Objective(s): To investigate the effect of miR-103 on the angiogenesis of ischemic stroke rats via targeting vascular endothelial growth factor (VEGF) at the molecular level. Materials and Methods: Rat models had received the middle cerebral artery occlusion (MCAO) or sham operation before grouping, and cell models of oxygen-glucose deprivation (OGD) were performed. FITC-dextran, matrigel, and ...
Background and Aims: Chronic lymphocytic leukemia (CLL) is the most common adult human leukemia. MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression. Research has shown that in CLL, microRNAs can have function as oncogenes or tumor suppressors. Some studies demonstrated that the expression of microRNA-93 (miR-93) and microRNA-330 (miR-330) have been changed in several can...
Acute lung injury (ALI) causes high mortality, but its molecular mechanisms are poorly understood. Acid aspiration is a frequent cause of ALI, leading to neutrophil sequestration, increased permeability, and deterioration of gas exchange. We investigated the role of platelet-neutrophil interactions in a murine model of acid-induced ALI. Acid aspiration induced P-selectin-dependent platelet-neut...
Multiple lung pathogens such as chemical agents, H5N1 avian flu, or SARS cause high lethality due to acute respiratory distress syndrome. Here we report that Toll-like receptor 4 (TLR4) mutant mice display natural resistance to acid-induced acute lung injury (ALI). We show that TLR4-TRIF-TRAF6 signaling is a key disease pathway that controls the severity of ALI. The oxidized phospholipid (OxPL)...
The Advanced Land Imager (ALI) is a multispectral sensor onboard the National Aeronautics and Space Administration Earth Observing 1 (EO-1) satellite. It has similar spatial resolution to Landsat-7 Enhanced Thematic Mapper Plus (ETM+), with three additional spectral bands. We developed new algorithms for estimating both land surface broadband albedo and leaf area index (LAI) from ALI data. A re...
Identifying immunocompromised women who are at risk of developing cervical cancer remains a challenge for clinicians. In an effort to identify the role HIV in carcinogenesis, this study evaluated levels normally downregulated oncomirs (miR-21, miR-146a, miR-155, miR-182, and miR-200c) upregulated tumor suppressors (miR-let-7b, miR-125b, miR-143, miR-145, p53 expression) associated with serum li...
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