www.ephysinnovation.com Electrophysiology Innovation Partnership e.V. Markwiesenstr. 55 72770 Reutlingen, Germany [email protected] Workshop Coordinators: H. R. Polder, npi electronic GmbH, [email protected] I. Herzberg, ALA Scientific Instruments [email protected] Pharmacology of two nicotinic acetylcholine receptor subtypes on insect CNS neurons studied with the Single-Electr...

INTRODUCTION: Our inability to record single cell activity with high resolution over a long period of time precludes fundamental understanding of nervous system functions, both under normal and pathological conditions. While the fabrication of current microand nano-electrodes has advanced our capabilities to perform long-term recordings, this has been at the expense of signal resolution due to ...

The impact of the convective fluid motion induced by the electric fields on the dielectrophoretic manipulation of particles is investigated theoretically and experimentally. By means of a simplified model a channel with a periodic array of microelectrodes we show that electroconvective flows induce the formation of traps for particles, providing a dynamical mechanism to control microparticles i...

Capillary ultrainicroeleetrodes were inserted into ventriculaimuscle fibers of dogs in ventricular fibrillation nnd action potentials obtained were compared with deflection.? of unipolar direct lead, adjoining; bipolar direct lead or other electrocardiograms taken simultaneously. In most stages of ventricular fibrillation neither synchronism nor any other regular time relationship could be foun...

This chapter will review recent progress in the application of microelectrode techniques to the study of a range of cell physiological problems in plant cells and microorganisms. Plant cells present a special set of problems for electrophysiology and other microelectrode methods, related principally to cell structure (Fig. 1). The past five years have been witness to an great expansion in the a...

Spatially separated electron donors and acceptors in sediment can be exploited by the so-called “cable bacteria.” Electric potential microelectrodes (EPMs) were constructed to measure the electric fields that should appear when cable bacteria conduct electrons over centimeter distances. The EPMs were needle-shaped, shielded Ag/AgCl half-cells that were rendered insensitive to redox-active speci...

Fluorescent dyes were used to mark and identify the tracks left by extracellular microelectrodes in neurophysiological experiments. Forty-two penetrations were made into the postcentral gyrus of 3 Macaque monkeys with electrodes coated with 1 of 5 fluorescent dyes (DiI, DiO, DiI-C5, PyPO, and Fast Blue). The electrodes were driven at rates ranging from 10 to 1000 microns/min, to a depth of abou...

Altlhoughi microelectrocle measurements lhave caused a good deal of confusion in the investigation of renal electrolyte transport (for literature see Ref. 4), we cannot do witlhout them. Knowledge of the electrical potential steps, whiclh the ions have to pass (luring their reabsorption, is indispensable for understanding the transport meclhanisms involved. Hence the development of more reliabl...

Recording a neural ensemble has been an extremely successful experimental paradigm allowing real-time interpretation of neural codes as well as the detection of dynamic changes within a process. In recent years, microfabricated electrodes have attracted a great deal of attention for recording neural ensembles with superior resolution and spatial density. A 3D microfabricated electrode is partic...