Key words: in situ stabilization, bioavailable PB, soil remediation This study was conducted to evaluate the effects of P, Mn oxide, and time on bioavailable Pb in five metal-contaminated soils or mine spoils in the absence or the presence of plants, and to evaluate the effect of those treatments on phytoavailability of Pb, Cd, and Zn. The addition of P or Mn oxide reduced bioavailable Pb compa...

AIMS High androgen levels are presumed by many to explain the male predisposition to coronary artery disease. However, natural androgens inhibit male atherosclerosis(1). Our aim was to determine whether levels of androgens differ between men with and without coronary artery disease. METHODS AND RESULTS Ninety male subjects (60 with positive, and 30 with negative coronary angiograms) were recr...

An in vitro digestion/Caco-2 cell model was used to assess iron bioavailability of twenty elite latematuring tropical maize varieties grown in three diverse agroecologies in West and Central Africa (WCA). Kernel-iron concentration of the varieties, averaged across locations, varied from 19.2 to 24.4 mg kg−1, while mean kernel-zinc concentration ranged between 19.4 and 24.6 mg kg−1. Significant ...

Vitamin D binding protein (DBP) and albumin are the important determinants of circulatory 25(OH)D in adults. Physiological function of vitamin D is particularly regulated by DBPs. Serum parathyroid hormone (PTH) is considered as the biological activity reader of circulating 25(OH)D. We therefore examined the relationships between serum total, free, and bioavailable 25(OH)D versus PTH in apparen...

long-term application of fertilizers containing p, especially organic fertilizers, usually increases the water soluble and available p of soil and at the same time may result in p accumulation in soil. organic fertilizers may also increase movement of p in the soil profile that could result in surface and ground water pollution. an experiment was conducted on field plots that received three app...

Nanotechnology has enabled significant advances in the areas of cancer diagnosis and therapy. The field of drug delivery is a sterling example, with nanoparticles being increasingly used for generating therapeutic formulations of poorly water-soluble, yet potent anticancer drugs. Whereas a number of nanoparticle-drug combinations are at various stages of preclinical or clinical assessment, the ...

PURPOSE Marimastat is an orally bioavailable inhibitor of matrix metalloproteinases. A phase I study was initiated to determine whether conventional doses of carboplatin and paclitaxel are tolerated when combined with marimastat and to assess the influence of marimastat on paclitaxel pharmacokinetics. EXPERIMENTAL DESIGN Three dose levels were evaluated. Marimastat (10 or 20 mg oral administr...

This review highlights the innovative anti-aging strategies through effective use of calcium supplements. With the advent of pharmacology, modern medical technology and scientific advances in food and nutrition, the longevity of human being significantly improved. However, living long or anti-aging does not make any sense unless people maintain excellent health and quality of life. Thus, mainta...

The guanine derivative antiviral drug acyclovir (ACV) is one of the oldest molecules put downing triumphant market until date, being commercially accessible in a variety dosage forms for oral, topical and parenteral administrations. Clinical purpose this better to new agents due its potential values such as suppression recurrence, security profile, negligible interactions inexpensive. ACV sligh...

Productivity in the Southern Oceans is iron-limited, and the supply of iron dissolved from aeolian dust is believed to be the main source from outside the marine reservoir. Glacial sediment sources of iron have rarely been considered, as the iron has been assumed to be inert and non-bioavailable. This study demonstrates the presence of potentially bioavailable Fe as ferrihydrite and goethite in...