The problem of output regulation for nonlinear control systems with guaranteed transient performances in the presence of uncertainties is discussed, where the nonlinear systems are nonaffine in the control. The fast dynamical controller with the highest output derivative in feedback loop is used, where the controller is proper and can be implemented without ideal differentiation. Two-time-scale...

A single-chain Fv (scFv) fragment derived from the murine antibody 4G7, specific for human lymphocyte CD19, was engineered for stability and expression in Escherichia coli in view of future use as a therapeutic protein. We compared two orthogonal knowledge-based procedures. In one approach, we designed a mutant with 14 single amino-acid substitutions predicted to correct destabilizing residues ...

Connection between the stability of quantum motion in random fields and quark confinement in QCD is investigated. The analogy between the fidelity and the Wilson loop is conjectured, and the fidelity decay rates for different types of quark motion are expressed in terms of the parameters which are commonly used in phenomenological and lattice QCD. PACS numbers: 12.38.Aw; 05.45.Mt The property o...

This paper deals with leader-following and leaderless consensus problems of high-order multi-input/multi-output (MIMO) multi-agent systems with unknown nonlinear dynamics in the presence of uncertain external disturbances. The agents may have different dynamics and communicate together under a directed graph. A distributed adaptive method is designed for both cases. The structures of the contro...

This paper presents a new observer based fuzzy terminal sliding mode controller design for a class of fractional order nonlinear systems. Robustness against uncertainty and disturbance, the stability of the close loop system and the convergence of both the tracking and observer errors to zero are the merits of the proposed the observer and the controller. The high gain observer is applied to es...

This paper is concerned with delay-dependent exponential stability analysis and stabilization for continuous-time T-S fuzzy Markovian jump systems with mode-dependent time-varying delay. By constructing a novel Lyapunov-Krasovskii functional and utilizing some advanced techniques, less conservative conditions are presented to guarantee the closed-loop system is mean-square exponentially stable....

In this paper an adaptive PID controller for Wind Energy Conversion Systems (WECS) has been developed. Theadaptation technique applied to this controller is based on Reinforcement Learning (RL) theory. Nonlinearcharacteristics of wind variations as plant input, wind turbine structure and generator operational behaviordemand for high quality adaptive controller to ensure both robust stability an...

XRN2 is a 5'-3' exoribonuclease implicated in transcription termination. Here we demonstrate an unexpected role for XRN2 in the DNA damage response involving resolution of R-loop structures and prevention of DNA double-strand breaks (DSBs). We show that XRN2 undergoes DNA damage-inducible nuclear re-localization, co-localizing with 53BP1 and R loops, in a transcription and R-loop-dependent proc...

This work was supported by CNPq. Dr. Spiazzi visit to the University of Campinas was supported by FAPESP. Abstract The effects of a non negligible source impedance, due to the presence of an input EMI filter, on the stability of Power Factor Preregulators with average current control are analyzed by using a State Space Averaged model. The modeling allows to derive a simple expression for the lo...

In many practical cases, the identification of a system is done using data meamred on the plant in closed loop with some contmller. In this paper, we show that the internal stability of the resulting model, in closed loop with the same controller, cannot always be guaranteed if this controller is unstable and/or nonminimum phase, and that the direct, indirect and joint input-output approaches o...