the aim of this study was to evaluate and compare the cytotoxicity induced by two resin-based sealers, 2seal and ah plus, in two osteoblast-like cell lines, mg-63 and saos-2. using sterile discs of both sealers in complete media, 24- and 72-h extracts were prepared. the extracts were exchanged with saos-2 or mg-63 cell culture media at 75% confluence, and after 24 h incubation, cell viability t...

objective(s): although many researchers have confirmed induction of germ cells from bone marrow mesenchymal stem cells (bmmscs), there are no reports that confirm spontaneous differentiation of germ cells from bmmscs. in this study, we have evaluated the effect of adult sertoli cell condition medium (sccm) as a mutative factor in the induction of germ cells from bmmscs. materials and methods: b...

background: the role of mesenchymal stem cell in cellular therapy is the subject of interest for many researchers. the differentiation potential of mscs and abilities in modulations of the recipient’s immune system makes them important cells in tissue regenerative studies. mscs by releasing the proinflammatory cytokines play important role in immunomodulatory systems; however the signaling path...