Lymphocyte blastogenic studies to autologous leukemia cells were carried out in 35 patients with adult acute leukemia. The effects of serum on this response and correlation with studies of general immunocompetence were studied. Twenty-five of 35 patients had positive blastogenesis. Nine patients with acute myelogenous leukemia had complete or partial abrogation of this response in autologous se...

Lymphocyte blastogenic studies to autologous leukemia cells were carried out in 35 patients with adult acute leukemia. The effects of serum on this response and correlation with studies of general immunocompetence were studied. Twenty-five of 35 patients had positive blastogenesis. Nine patients with acute myelogenous leukemia had complete or partial abrogation of this response in autologous se...

Objective: The purpose of this research is to examine the relationship between FLT3 mutation and hematological indices clinical correlates in patients with severe myelogenous leukemia & acute lymphoblastic leukemia. Study Design: Descriptive Study. Place Duration: Diagnostic Laboratory Liaquat university Medical health sciences jamshoro Hyderabad. January 2021 December 2021. Methods: Total ...

there have been much speculation and debate concerning the effect of electromagnetic fields (emf) on body systems. various reports have implicated excessive exposure to emf to certain forms of leukemia. it has also been reported that emf may cause alteration in the levels of certain macro- and micro-nutrients such as copper, zinc, selenium, calcium and iron. we have undertaken this study to det...

Viral infections especially herpes virus and varicella zoster are common complications in patients with hematologic malignancies. The spectrum of infectious during after dasatinib therapy not known. I report here recurrent labialis two chronic myeloid leukemia cases treated dasatinib.

Objective(s):Sulfur mustard (SM) was used by the Iraqi army against the Iranian troops in the Iran-Iraq war from 1983–1988. This chemical gas affects different organs including the skin, lungs and the hematopoietic system. Any exposure to SM increases the risk of chromosomal breaking, hyperdiploidy and hypodiploidy. Studies have shown that the risk for acute myeloblastic and lymphoblastic leuke...

Leukemia Cutis (LC) is a rare extramedullary cutaneous manifestation of leukemia that varies in terms clinical presentation, type, and timing presentation relation to systemic leukemia. LC typically presents following diagnosis during an active flare or relapse. An estimated 3.7% patients with Acute Myeloid (AML) develop LC. A 61-year-old male poorly controlled HIV presented rash began one mont...

Thirteen previously untreated patients aged 70 and above with acute nonlymphocytic leukemia were treated with aclarubicin (ACR) alone. Among 10 cases (3, acute myelocytic leukemia; 4, acute myelomonocytic leukemia; 2, acute monocytic leukemia; and one, acute erythroleukemia) in which an evaluation was possible, 5 cases (3, acute myelomonocytic leukemia; and 2, acute monocytic leukemia) obtained...

Background: This Cross sectional comparative study was performed to compare the mean fluorescence intensity of cluster of differentiation 45 between healthy individuals and patients with acute lymphoblastic leukemia. Patients and methods: Thirty three healthy individuals (mean age 11 years) and 41 patients with B cell acute lymphoblastic leukemia (mean age 7 years) were enrolled in the study...

Hairy-cell leukemia (HCL) is a CD20+ indolent B-cell cancer in which BRAF V600E kinase–activating mutation plays pathogenetic role. In clinical trials involving patients with refractory or relapsed HCL, the targeting of oral inhibitor vemurafenib led to response 91% patients; 35% had complete response. However, median relapse-free survival was only 9 months after treatment stopped.