reduction of methoxyketon 1 by nabh4 gives methoxyketol 2. allthough acetate and tosylate of this alchohol were not seprated, benzoate ester was isolated. reduction of ketol 2 by lialh4 gives alchohol 4. ketol 9 does not react with methyl magnesium iodide, but methoxyketon 1 react with both methyl magnesium iodide and phenyl magnesium iodide gives corresponding hydrocarbons. keton 13 with pheny...

The efficacy of iodide and thyroxine in ameliorating the several deficiencies occasioned by thyroidectomy in male and female rats was compared in order to obtain indirect evidence for extrathyroidal thyroxine formation. More direct refutation of the opposing concept that iodide simulates the action of thyroxine was also sought in experiments with propylthiouracil (PTU) and tribromothyronine. In...

Hexakis(dimethyl sulfoxide)scandium(III) iodide, [Sc(OS(CH(3))(2))(6)]I(3) contains centrosymmetric hexasolvated scandium(III) ions with an Sc-O bond distance of 2.069(3) angstroms. EXAFS spectra yield a mean Sc-O bond distance of 2.09(1) angstroms for solvated scandium(III) ions in dimethyl sulfoxide solution, consistent with six-coordination. Raman and infrared absorption spectra have been re...

Autosomal dominant myotonia congenita is an inherited disorder of skeletal muscle caused by mutations in a voltage-gated Cl- channel gene (CLCN1, 7q35). Here, we report that a mutation predicting the substitution of Gly 230 by glutamic acid (G230E) between segments D3 and D4 dramatically alters the pore properties of a recombinant human muscle Cl- channel (hCIC-1) expressed in a mammalian cell ...

We present the case of a 61-year-old man who underwent I-123 metaiodobenzylguanidine (MIBG) scintigraphy based on clinical suspicion of pheochromocytoma. The study was nondiagnostic secondary to diffuse muscle uptake. On review of his medications, the patient was found to be taking mirtazapine, a tetracyclic antidepressant (Remeron). We hypothesize that the MIBG biodistribution was altered by m...

In order to study the chemical oscillatory behavior and mechanism of a new chlorine dioxide-iodide ion-methyl acetoacetate reaction system, a series of experiments were done by using UV-Vis and online FTIR spectrophotometric method. The initial concentrations of methyl acetoacetate, chlorine dioxide, potassium iodide, and sulfuric acid and the pH value have great influence on the oscillation ob...

BACKGROUND The heart-to-mediastinum ratio (HMR) of (123)I-metaiodobenzylguanidine (MIBG) showed variations among institutions and needs to be standardized among various scinticamera-collimator combinations. METHODS A total of 225 phantom experiments were performed in 84 institutions to calculate cross-calibration coefficients of HMR. Based on phantom studies, a conversion coefficient for each...

Perovskite solar cells have progressed very steadily, reaching power conversion efficiencies (PCE) beyond 20% while also improving their lifetimes up to 10,000 h. A large number of cell architecture and materials for active, transporting electrode layers been used, either in blends or nanostructured layers. In this article, a set perovskite designed, fabricated characterized with special focus ...