نتایج جستجو برای: interferon type i
تعداد نتایج: 2250534 فیلتر نتایج به سال:
Background the crucial role of hyperactivation IFN I signaling pathway has been proved in pathogenesis dermatomyositis. genes and chemokines activity vary according to subtype inflammatory myopathies. type 1 signature could be measured using different blood, skin muscle tissue [1]. Objectives evaluate IFN-score children with dermatomyositis compare disease Methods 15 patients (5 boys 10 girls) ...
In this study we have examined the density of HLA class I protein display on the hepatocytes of patients with HBe antigen (HBeAg) or anti-HBe (HBeAb) positive chronic hepatitis B virus (HBV) infection and related this to the level of interferon activation of these cells determined by measuring hepatic oligo 2-5A synthetase activity. In HBeAg positive patients the density of HLA class I (HLA-I) ...
BACKGROUND High-density lipoprotein (HDL) protects the artery wall by removing cholesterol from lipid-laden macrophages. However, recent evidence suggests that HDL might also inhibit atherogenesis by combating inflammation. METHODS AND RESULTS To identify potential antiinflammatory mechanisms, we challenged macrophages with lipopolysaccharide, an inflammatory microbial ligand for Toll-like re...
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