نتایج جستجو برای: immune mediated disease
تعداد نتایج: 2013882 فیلتر نتایج به سال:
Psoriasis was used as a model to analyze the pathogenetic pathways of immune-mediated inflammatory diseases, and the results of bioinformatic, molecular-genetic and proteomic studies are provided. Cell mechanisms, common for the pathogenesis of psoriasis, as well as Crohn's disease, are identified. New approaches for immune-mediated diseases are discussed.
Psoriasis is a chronic, recurrent, immune-mediated inflammatory disease that affects 2%–3% of the world's population. It related to genetic vulnerability, autoimmunity, mental health, and environmental factors. Pathogenesis highly linked abnormal interactions between innate immunity, T lymphocytes, keratinocytes. Maresin 1 (Mar1) one EPA-derived metabolites with substantial anti-inflammatory ac...
Pemphigus vulgaris (PV) is a rare autoimmune blistering disorder that primarily affects the skin and mucous membranes. Conventional treatments for PV, such as corticosteroids immunosuppressive agents, have limitations in terms of efficacy long-term safety. Monoclonal antibody therapy, specifically rituximab, has emerged promising therapeutic approach management PV. This review article provides ...
Statin-induced necrotizing autoimmune myopathy is an immune-mediated related to the use of statins. It a very rare disease, which usually presents with proximal muscle weakness and frank elevation in creatine kinase levels. Stopping statin immunosuppressive therapy are considered mainstay therapy. Herein, we present case 75-year-old patient statin-induced based on presence weakness, magnetic re...
BACKGROUND Subarachnoid hemorrhage (SAH) is a devastating cause of stroke, occurring in relatively young people. It has been suggested that some immune-mediated diseases may be associated with an increased risk of SAH. METHODS We analysed a database of linked statistical records of hospital admissions and death certificates for the whole of England (1999-2011). Rate ratios for SAH were determ...
Borna disease virus infection of Lewis rats results in an immune-mediated disease associated with transient meningoencephalitis and persistent viral infection. In the acute phase of disease, perivascular immune cell infiltrates consisted of CD4 + and CD8 + T cells, macrophages and NK cells with peak expression of mRNAs encoding the cytokines IL1alpha, IL2, IL6, TNFalpha, and IFNgamma. In the ch...
Immune-mediated oral disorders are characterised by their chronicity, and some are refractory to treatment. Interference RNA (iRNA) has been implicated in the underlying mechanism of such immune-mediate oral and refractory inflammatory oral diseases. iRNA-based understanding of the mechanism in these diseases may help to produce non-invasive diagnostic methodologies and treatment modalities of ...
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