Among the congenital abnormalities of the urinary tract, the term hypoplastic kidney is one of the least well defined and also one of the most widely used. Certain abnormal structures are sometimes called hypoplastic kidneys and certain abnormal kidneys which we term hypoplastic are called by some aplastic (even agenetic) kidneys, dysplastic, congenital atrophic, miniature, or infantile kidneys...

Congenital hypoplastic anemia is a rare disease characterized by a normochromic, normocytic anemia, a deficiency of erythroblasts in the marrow, and normal leukocyte and platelet counts. The disease usually is treated successfully with corticosteroid therapy; however, some patients become refractory to corticosteroids and must receive washed, packed red blood cell transfusions. The management a...

Some patients with hypoplastic marrow disorders, including aplastic anemia (AA), are at risk for clonal evolution to myelodysplastic syndromes (MDS) and leukemia. Magnetic resonance imaging (MRI) of marrow of the spine, pelvis, and femurs was performed in 24 patients with hypoplastic marrow disorders. In 12 patients (three AA, nine MDS) MRI was compatible with the clinical and biopsy diagnoses ...

A review of 63 patients with 45X karyotype (Turner's syndrome) admitted to a hospital from 1972 to 1985 showed that 20 (32%) had one or more major cardiac malformations (mostly coarctation and aortic stenosis). Four (20%) died in the neonatal. One infant had mitral stenosis and severe aortic stenosis and died at the age of 35 days. The three (15%) other patients who died had a typical hypoplast...

OBJECTIVE Thumb problems are common in some health professionals such as physical therapists. The purpose of this case-control study is to investigate the influence of clinical experience and different mobilization techniques on the kinematics of the thumb. METHODS Twenty-three participants without exposure to manual techniques (the Novice Group) and fifteen physical therapists with at least ...

its comparative rarity may be indicated by the fact that in a review of the literature for the ensuing fifty-two years (Stieve 1916) only thirty-nine cases were collected. Lapidus, Guidotti and Coletti (1943) discovered six cases while examining 75,000 men drafted to an American Army centre. These workers quoted a statement by Dr M. Pomeranz. radiologist of the Hospital for Joint Diseases in Ne...

PURPOSE Interphalangeal joint stabilization often is performed concomitantly with tendon transfers that restore key pinch (lateral pinch) to the paralyzed thumb. The goal of this study was to measure the effect of interphalangeal joint stabilization via percutaneous pin fixation on the thumb-tip force produced by the flexor pollicis longus (FPL). METHODS We applied 10 N of force to the tendon...

This article reports a systematic research effort aimed at establishing a normative database of thumb circumduction range of motion (ROM) and related kinematic characteristics in vivo while examining the effects of anthropometry, gender, and direction of rotation. Twenty-eight (14 men, 14 women) anthropometrically diverse participants performed maximum voluntary thumb circumductions as the traj...

The condition of chronic instability of the MP (metacarpophalangeal) joint of the thumb, may be the resultant of chronic strain of the ulnar collateral ligament of the MP joint. This condition was described in Scottish gamekeepers who used to kill hunted animals by a special manoeuvre subjecting the thumb to extension abduction force, and was termed "Gamekeeper's Thumb" (Campbell, 1955). Nowada...

Background: The function of the thumb is critical to overall hand function. Uniquely endowed with anatomic features that allow circumduction and opposition, the thumb enables activities of pinch, grasp, and fine manipulation that are essential in daily life. Destruction of the thumb secondary to trauma represents a much more significant loss than would result from loss of any other digit. There...