نتایج جستجو برای: human gastric carcinoma

تعداد نتایج: 2023405  

2015
YASUMICHI YAGI SHOZO SASAKI AKEMI YOSHIKAWA YUJI TSUKIOKA WATARU FUKUSHIMA TAKASHI FUJIMURA HISASHI HIROSAWA RYOHEI IZUMI KATSUHIKO SAITO

Metastases to the gastrointestinal tract rarely occur in breast cancer except in invasive lobular carcinoma. The present study reports a rare case of metastatic gastric cancer from invasive ductal carcinoma (IDC) of the breast mimicking primary gastric linitis plastica. A 51-year-old premenopausal female, who had a history of partial mastectomy for right breast cancer at the age of 40, was refe...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2001
A Vecchione H Ishii Y H Shiao F Trapasso M Rugge J F Tamburrino Y Murakumo H Alder C M Croce R Baffa

PURPOSE Loss of heterozygosity (LOH) involving the short arm of chromosome 8 (8p) is a common feature of the malignant progression of human tumors, including gastric cancer. We have cloned and mapped a candidate tumor suppressor gene, FEZ1/LZTS1, to 8p22. Here we have analyzed whether FEZ1/LZTS1 alterations play a role in the development and progression of gastric carcinoma. EXPERIMENTAL DESI...

2011
Ken-Sheng Cheng Hui-Ling Tang Jen-Wei Chou Cheng-Ju Yu Shi-Seng Tsou Fu-Tsan Chou

BACKGROUND/AIMS The incidence of gastric remnant carcinoma does not decrease after partial gastrectomy The aim of this study was to evaluate the clinical features and prognosis of gastric remnant carcinoma after treatment. METHODOLOGY Among 412 gastric carcinoma patients who were admitted to our hospital 21 were found to have gastric remnant carcinoma. We analyzed their clinicopathological fe...

2005
Miki Ohta Keisuke Tateishi Fumihiko Kanai Hirotsugu Watabe Shintaro Kondo Bayasi Guleng Yasuo Tanaka Yoshinari Asaoka Amarsanaa Jazag Jun Imamura Hideaki Ijichi Tsuneo Ikenoue Masataka Sata Makoto Miyagishi Kazunari Taira Minoru Tada Takao Kawabe Masao Omata

The activation of Hedgehog (Hh) signaling has been implicated in the growth of various tumor types, including gastric carcinoma. However, the precise mechanisms of Hh activation and suppression of tumor growth by the blockade of Hh signaling in gastric carcinoma cells remain unknown. The aim of this study was to elucidate the mechanism of abnormal Hh signaling and the key molecules contributing...

2015
SU-ZUAN CHEN HUAI-QI YAO SEN-ZHI ZHU QIU-YUAN LI GUANG-HUA GUO JING YU

The present report investigated the correlation between the expression levels of matrix metalloproteinase (MMP)-9 in gastric carcinoma patients and the clinicopathological characteristics. Forty-five samples of gastric carcinoma and distal gastric mucosa tissue, and 10 samples of healthy gastric mucosa tissue were analyzed using semi-quantitative polymerase chain reaction, as well as immunohist...

2013
XUEFEI SHI XIAO LI LIN CHEN CHUNHUI WANG

Somatostatin (SST) is a gut peptide that is able to inhibit the growth of tumor cells in gastric cancer and other types of cancer. The present study investigated the mRNA and protein levels of SST and SST receptors (SSTRs) in human gastric cancer, and detected the DNA methylation of the SST promoter. The protein levels of SST were detected using a radioimmunoassay in 102 human gastric tissue sp...

Journal: :JPMA. The Journal of the Pakistan Medical Association 2005
Muhammad Iqbal Khan Muhammad Tariq Baqai Murtaza Bukhari Ramiz Iqbal Hashmi

OBJECTIVE To study the five years survival rate after resection for gastric carcinoma. METHODS Fifty six patients with gastric carcinoma in different stages were followed up for 5 years after gastric surgery to see recurrence, complications and survival rate. RESULTS Of the 56 patients, 6 underwent total gastrectomy, 50 partial gastrectomy, 7 Billroth I and 43 modified DI resection with Bil...

Journal: :Molecules 2011
Mariano Walter Pertino Cristina Theoduloz Jose Antonio Palenzuela Maria del Mar Afonso Erdem Yesilada Francisco Monsalve Paulo González Daniel Droguett Guillermo Schmeda-Hirschmann

New diterpenylquinones, combining a diterpene diacid and a naphthoquinone, were prepared from junicedric acid and lapachol. The new derivatives were assessed as gastroprotective agents by the HCl-EtOH-induced gastric lesions model in mice as well as for basal cytotoxicity on the following human cell lines: Normal lung fibroblasts (MRC-5), gastric epithelial adenocarcinoma (AGS), and hepatocellu...

Journal: :International journal of clinical and experimental pathology 2014
Wenjin Zhang Weihua Xiao Haifen Ma Mingfei Sun Hongtan Chen Shusen Zheng

Mixed adenoneuroendocrine carcinoma (MANEC) is a rare disease, which mostly occurs in the gastrointestinal tract and pancreas. Here we report a case of gastric MANEC with tri-lineage differentiation in which only the neuroendocrine component had metastasized to the liver. Liver and gastric masses were detected by abdominal computed tomography, and the preoperative relationship between liver and...

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