BACKGROUND Homeostasis model assessment of insulin resistance (HOMA-IR) is a surrogate estimate of directly measured insulin resistance that been robustly proven to be associated with diabetes and cardiovascular disease. The purpose of this study was to evaluate the use of several simple indicators to identify postmenopausal women with insulin resistance estimated by HOMA-IR. METHODS We recru...

Introduction and aim. Thyroid hormones play an important role in glucose metabolism as many metabolic events. The aim of our study is to evaluate the relationship between subclinical hypothyroidism (SCH) insulin resistance, especially obese women. Material methods. Newly diagnosed SCH patients with body mass index (BMI) ≥30 who applied outpatient clinic March 2021 October 2021, euthyroid women ...

In a recent study of insulin resistance (IR), insulin deficiency and their relationship with obesity in children using homeostasis model assessment (HOMA) values in a population-based setting, Nishimura et al. showed that increased body mass index (BMI) was significantly correlated with increased IR in boys, but not in girls. The authors concluded that increases in BMI could have far more diver...

AIMS Previous studies have reported that insulin resistance plays an important role in the progression of atherosclerosis. However, the relationship between insulin resistance and coronary plaque instability is not well established. The purpose of this study was to assess the relationship between insulin resistance and coronary plaque characteristics identified by optical coherence tomography (...

Background: Previous study had found that adherence of patient Diabetes type-2 in moderate to vigorous continuous exercise was poor. Meanwhile regularly needs control fasting plasma glucose T2DM. Exercise interval (EMI) shows a significant effect reduce insulin resistance metabolic syndrome patients. But, studies find the EMI or EMC muscle receptor distribution are still limited. So, purpose th...

OBJECTIVE To assess differences in insulin sensitivity and beta-cell function between nondiabetic premenopausal or early perimenopausal non-Hispanic white women and African American, Chinese American, Japanese American, and non-Mexican-American Latino women. RESEARCH DESIGN AND METHODS Homeostasis model assessments (HOMAs) of insulin sensitivity (HOMA%S) and beta-cell function (HOMA%beta) wer...

Adipose tissue-derived hormone leptin plays a functional role in glucose tolerance through its effects on insulin secretion and insulin sensitivity which also represent the risk factors for nonalcoholic fatty liver disease (NAFLD). The present study explored the gender specific association of serum leptin and insulinemic indices with NAFLD in Bangladeshi prediabetic subjects. Under a cross-sect...

objective: the aim of the present study is assessment of insulin resistance (ir) in obese women by tyg-index and compared with the homa-ir index. materials and methods: this cross-sectional study was performed on 61 obese women aged 18-45 years. weights, height, waist circumference (wc) were measured and body mass index (bmi) was calculated and recorded. a sample of fasting serum was collected ...

INTRODUCTION Prevalence of insulin resistance and the metabolic syndrome has been reported to be high in rheumatoid arthritis (RA) patients. Tumor necrosis factor (TNF), a pro-inflammatory cytokine with a major pathogenetic role in RA, may promote insulin resistance by inducing Ser312 phosphorylation (p-Ser312) of insulin receptor substrate (IRS)-1 and downregulating phosphorylated (p-)AKT. We ...

BACKGROUND Visceral obesity is positively related to insulin resistance. The nature of the relationship between waist circumference and insulin resistance has not been known in Japanese populations. This study examined the relationship between waist circumference and insulin resistance and evaluated the optimal cutoff point for waist circumference in relation to insulin resistance in middle-age...