In this study, age-dependent histological changes in the kidneys of Brown Norway rat, a strain useful for conducting aging research, were evaluated. Examination was performed at 3, 12, 18, 24 and 30 months of age. Sclerotic and hypertrophic changes of the glomeruli were observed, and quantitative scores of these changes persistently increased with age. A marginal increase in scores was observed...

The thyroid has been examined histologically in 77 cases of cirrhosis of the liver and in an equal number of control cases. Contrary to expectation, no difference was found between the incidence or the severity of lymphocytic infiltration of the thyroid in the two groups. A conspicuous fibrosis or ;cirrhosis' of the thyroid, not related to lymphocytic infiltration, was associated with cirrhosis...

AN attempt has been made to find the cells of origin and the time of origin during development of the vitreous hyaluronic acid. The adult vitreous body of those species so far examined seems to owe its characteristic jelly-like properties to the presence of small amounts of an insoluble collagen-like protein laid down in fibrous lamellae and a low concentration of hyaluronic acid. Earlier work ...

To obtain detailed information about the histological changes occurring in the mouse nipple during the reproductive cycle, we examined and quantified the S-phase of cell by immunohistochemical staining with bromodeoxyuridine (BrdU), and analysed histologically the subepithelial fibrous elements. The nipple markedly increased in size dramatically on days 15-18 of pregnancy. The densities of cell...

Adult Mice (BWt. 30 gms and 40gms) were treated at a 5mg\kgBWt. and 10 mg/kg BWt. of Ethidium Bromide for 10 days in drinking water. Control animals were given equal dose of deionised water. Quantitative and qualitative changes were studied in Spleen. The following features were evaluated: the overall cellularity of the spleen was noticed. The changes were characterised by, injury to spleen tis...