Fundamental knowledge about the composition of intestinal fluids in paediatric populations is currently unavailable. This study aimed to characterise gastric and fluid from populations. Gastric samples were obtained during routine clinical endoscopy patients at a large teaching hospital. These characterised measure pH; buffer capacity; osmolality; bile acid concentration composition. A total 55...

Helicobacter pylori colonized the highly acidic human gastric mucosa. At pH 3.0 to 7.0, this bacterium maintained a nearly neutral internal pH. Its membrane potential changed reciprocally with the pH gradient so that a relatively constant proton motive force was maintained. Possible, the capacity to maintain an appropriate transmembrane ionic gradient at a low pH contributes to the pathogenic p...

At the gastroesophageal junction, most vertebrates possess a functional lower esophageal sphincter (LES) which may serve to regulate the passage of liquids and food into the stomach and prevent the reflux of gastric contents into the esophagus. Snakes seemingly lack an LES and consume meals large enough to extend anteriorly from the stomach into the esophagus thereby providing the opportunity f...

In the first part of this investigation 33 subjects were investigated. Ten (nos. I to 10) had previously undergone operations for peptic ulcer (eight Billroth II and one Billroth I partial gastrectomies and one gastroenterostomy) (Table I). Seven patients (nos. 11 to 17) suffered from idiopathic steatorrhoea (Table II). Eight patients (nos. 18 to 25) had pernicious anaemia, untreated or treated...

In the first part of this investigation 33 subjects were investigated. Ten (nos. I to 10) had previously undergone operations for peptic ulcer (eight Billroth II and one Billroth I partial gastrectomies and one gastroenterostomy) (Table I). Seven patients (nos. 11 to 17) suffered from idiopathic steatorrhoea (Table II). Eight patients (nos. 18 to 25) had pernicious anaemia, untreated or treated...

The role of secretin in the inhibition of gastric acid secretion that occurs during acidification of the gastric lumen was studied in nine healthy men. Gastric acid secretion was stimulated by 500-ml meals of 8% peptone solution, and the pH of the stomach was maintained at 5.5, 2.5, or 2.0 by intragastric titration. The increase in plasma secretin was measured, after extraction, by a new secret...

BACKGROUND AND AIMS The success of Helicobacter pylori eradication regimens depends on gastric pH, inflammation, and mucus thickness. Our aim was to investigate the effects of acid secretion, inflammation, and mucolysis on gastric antibiotic transfer. SUBJECTS AND METHODS A total of 134 anaesthetised rats were given metronidazole, amoxicillin, or clarithromycin intravenously and gastric conte...

BACKGROUND Seroepidemiological and clinical studies suggest that Helicobacter pylori may cause iron deficiency anaemia (IDA) in the absence of peptic lesions by undefined mechanisms, which still remain to be fully elucidated. Gastric acidity and ascorbic acid (AA) promote iron absorption. AA is lowered in the presence of H pylori infection. H pylori can cause atrophic body gastritis with achlor...

Background: Seroepidemiological and clinical studies suggest that Helicobacter pylori may cause iron deficiency anaemia (IDA) in the absence of peptic lesions by undefined mechanisms, which still remain to be fully elucidated. Gastric acidity and ascorbic acid (AA) promote iron absorption. AA is lowered in the presence of H pylori infection. H pylori can cause atrophic body gastritis with achlo...