objective: the role of wnt signaling and its antagonist; secreted frizzled related protein type 4 (sfpr4) was reported in rodent ovarian follicular development. this study examines immunolocalization of sfrp4 in ovaries of polycystic ovary (pco) rat model and evaluates its role in follicular growth arrest and its premature differentiation. materials and mathods: pco was induced with daily admin...

Follicular T-to-be Helper T (Th) cell identity may not be for life. According to a pair of studies from Zaretsky et al. (page 991) and King and Mohrs (page 1001), Th2 cells can turn into follicular T cells when duty calls. Many immunologists consider each Th cell subset to be its own distinct class. The same is true of follicular T cells, CD4 + cells found in the B cell follicles and germinal c...

Ovarian tissue freezing or cryopreservation might be the only acceptable method for preserving the young women fertility, before radiotherapy or chemotherapy. This technology might be used for patients with recurrent ovarian cysts or endometriosis, without ovarian stimulation. Many efforts have made to improve cryopreservation conditions that should be seriously considered for cancer patients. ...

Bovine follicular oocytes matured in vitro were fertilized in vitro using epididymal spermatozoa from five different bulls and then cultured to the blastocyst stage in vitro. The fertilization rate, based on one pair of pronuclei and presence of one sperm tail, ranged from 55.2 to 64.3%. Embryo development (cleavage to blastocyst stage) ranged from 21.4 to 31.0% of the cultured ova reaching 8 c...

OBJECTIVE To determine the clinicopathologic features and the disease course of patients with follicular mycosis fungoides (MF). DESIGN A multicenter, 14-year, retrospective cohort analysis. SETTING Dutch Cutaneous Lymphoma Group. PATIENTS Fifty-one patients with the clinicopathologic features of follicular MF with (n = 49) or without (n = 2) associated follicular mucinosis. Follow-up dat...

In female pigs feeding level has important effects on reproductive performance. This review is focused on the follicular development after low and high feeding levels during the luteal phase in gilts. Although aspects of diet composition seem to have a role in regulating reproductive performance, the most important aspect appears to be the plane of nutrition. Similar effects are described durin...

Follicular atresia is a key event in the selection of the ovulatory follicles and occurs during all developmental stages. The aims of the study were to evaluate the follicular population as well as the rates of follicular recruitment and atresia in different strains of mice. Ovaries were obtained from four strains of mice: G1/ Swiss, G2/ F1 Swiss×C57BL/6, G3/ inbred strain C57BL/6, and G4/ F1 C...

Carcinoid tumours of the common bile duct represent an extremely rare entity. Similarly, primary follicular lymphomas of the ampulla of Vater constitute an infrequent neoplasia. Herein, we report the first case of a synchronous development of a carcinoid tumour of the common bile duct and an ampullary follicular lymphoma that was treated surgically with a Whipple's procedure, due to inability t...

Treatment of neonatal mice with urethane (0-5 or 0-75 mg/g body wt, i.p.) caused a lack of follicular development beyond the primordial stage. An effect of the thymus on ovarian development is inferred.