Breast cancer remains the second most common cause of cancer death in the United States. Several studies have identified cohorts of women at higher than average risk to develop this disease. These are women who are exposed to high levels of endogenous or exogenous estrogens, those with a family history of breast cancer, and those who harbor benign breast disease or genetic mutations that predis...

Dilated plugged acini in the pancreas are one of the fundamental histological features in 'fibrocystic disease.' Andersen (1938), however, in her original article on 'Fibrocystic Disease in the Pancreas in Relation to Celiac Syndrome' pointed out that cystic acini occur in a large number of children, and she was careful to confine her diagnosis of fibrocystic disease to cases where more than 90...

Dilated plugged acini in the pancreas are one of the fundamental histological features in 'fibrocystic disease.' Andersen (1938), however, in her original article on 'Fibrocystic Disease in the Pancreas in Relation to Celiac Syndrome' pointed out that cystic acini occur in a large number of children, and she was careful to confine her diagnosis of fibrocystic disease to cases where more than 90...

A 52-year-old woman with infiltrating ductal carcinoma of the left breast of clinical stage IIA is reported. Tumorectomy and selective biopsy of the sentinel lymph node (SLN) were performed. Mammography showed dense breasts with an image of poorly defined asymmetric density joining the inferior quadrants of the left breast which corresponded to a suspicious solid nodule of 18mm×11mm on ultrasou...

INTRODUCTION: Pre-pectoral breast reconstruction is an emerging technique with potential benefits that include reduced pain, early patient recovery and no hyperanimation. There are studies reporting on clinical outcomes with pre-pectoral technique [PP] and comparing it to the dual plane technique [DP] in breast reconstruction. The goal of this study is to provide an early assessment of outcomes...

OBJECTIVE To determine the impact of facility-based semi-intensive and home-based intensive counselling in improving exclusive breast-feeding (EBF) in a low-resource urban setting in Kenya. DESIGN A cluster randomized controlled trial in which nine villages were assigned on a 1:1:1 ratio, by computer, to two intervention groups and a control group. The home-based intensive counselling group (...

This study aimed to assess the trajectory of breast displacement in 3 dimensions during walking and running gait, as this may improve bra design and has yet to be reported. Fifteen D-cup participants had reflective markers attached to their nipples and trunk to monitor absolute and relative breast displacement during treadmill walking (5 kph) and running (10 kph). During the gait cycle, the bre...

BACKGROUND AND OBJECTIVE Forensic testimony in alleged child pornography cases commonly asserts that Tanner stage (TS) 4 breast development, characterized by secondary mounding of the areola that is obliterated in TS 5, is evidence of age <18 years. Clinical experience does not support this notion, but there are no relevant studies. We sought to estimate how frequently TS 4 might be interpreted...

Benign breast disease (BBD) is a risk factor for breast cancer and may have a heritable component. Deficient DNA repair has been implicated in breast cancer etiology and may exert its effect before BBD, a known precursor. The association between allelic variants in DNA repair genes and BBD was examined in a cohort of women in Washington County, Maryland. BBD was defined by two criteria: (a) a p...