نتایج جستجو برای: excitability

تعداد نتایج: 15194  

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2013
Jesper Ericsson Marcus Stephenson-Jones Juan Pérez-Fernández Brita Robertson Gilad Silberberg Sten Grillner

The functions of the basal ganglia are critically dependent on dopamine. In mammals, dopamine differentially modulates the excitability of the direct and indirect striatal projection neurons, and these populations selectively express dopamine D1 and D2 receptors, respectively. Although the detailed organization of the basal ganglia is conserved throughout the vertebrate phylum, it was unknown w...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 1996
J R Moyer L T Thompson J F Disterhoft

Time-dependent, learning-related changes in hippocampal excitability were evaluated by recording from rabbit CA1 pyramidal neurons in slices prepared at various times after acquisition of trace eyeblink conditioning. Increased excitability (reduced postburst afterhyperpolarizations and reduced spike-frequency adaptation) was seen as early as 1 hr after acquisition to behavioral criterion, was m...

Journal: :Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2015
Christian Leukel Wolfgang Taube Jörn Rittweger Albert Gollhofer Michel Ducos Tobias Weber Jesper Lundbye-Jensen

OBJECTIVES Joint immobilization has previously been shown to modulate corticospinal excitability. The present study investigated changes in the excitability of distinct fractions of the corticospinal pathway by means of conditioning the H-reflex with transcranial magnetic stimulation (TMS) of the primary motor cortex (Hcond). This method allows assessment of transmission in fast (monosynaptic) ...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2007
Darrin H Brager Daniel Johnston

Bidirectional changes in synaptic strength are the proposed cellular correlate for information storage in the brain. Plasticity of intrinsic excitability, however, may also be critical for regulating the firing of neurons during mnemonic tasks. We demonstrated previously that the induction long-term potentiation was accompanied by a persistent decrease in CA1 pyramidal neuron excitability (Fan ...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2010
Edwin Santini James T Porter

Growing evidence indicates that the activity of infralimbic prefrontal cortex (IL) is critical for inhibiting inappropriate fear responses following extinction learning. Recently, we showed that fear conditioning and extinction alter the intrinsic excitability and bursting of IL pyramidal neurons in brain slices. IL neurons from Sprague Dawley rats expressing high fear had lower intrinsic excit...

Journal: :Journal of psychosomatic research 2011
Joachim Liepert Thomas Hassa Oliver Tüscher Roger Schmidt

BACKGROUND Patients with a psychogenic paresis have difficulties performing voluntary movements. Typically, diagnostic interventions are normal. We tested whether patients with a psychogenic lower limb paresis exhibit abnormal motor excitability during motor imagery or movement observation. METHODS Transcranial magnetic stimulation (TMS) with single and paired pulses was used to explore motor...

Journal: :Journal of applied physiology 2006
Gabrielle Todd Stanley C Flavel Michael C Ridding

Repetitive transcranial magnetic stimulation of the motor cortex (rTMS) can be used to modify motor cortical excitability in human subjects. At stimulus intensities near to or above resting motor threshold, low-frequency rTMS (approximately 1 Hz) decreases motor cortical excitability, whereas high-frequency rTMS (5-20 Hz) can increase excitability. We investigated the effect of 10 min of interm...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 1998
B G Schreurs P A Gusev D Tomsic D L Alkon T Shi

Intradendritic recordings in Purkinje cells from a defined area in parasaggital slices of cerebellar lobule HVI, obtained after rabbits were given either paired (classical conditioning) or explicitly unpaired (control) presentations of tone and periorbital electrical stimulation, were used to assess the nature and duration of conditioning-specific changes in Purkinje cell dendritic membrane exc...

Journal: :Journal of neurophysiology 2004
Robert H Cudmore Gina G Turrigiano

Neuronal excitability has a large impact on network behavior, and plasticity in intrinsic excitability could serve as an important information storage mechanism. Here we ask whether postsynaptic excitability of layer V pyramidal neurons from primary visual cortex can be rapidly regulated by activity. Whole cell current-clamp recordings were obtained from visual cortical slices, and intrinsic ex...

Journal: :Stroke 2004
J Liepert T Kucinski O Tüscher F Pawlas T Bäumer C Weiller

BACKGROUND AND PURPOSE The cerebellum has an influence on motor excitability. We investigated if the location of a cerebellar infarction was crucial for changes of motor cortex excitability and if the electrophysiological findings were correlated with motor performance. METHODS Transcranial magnetic stimulation was applied to study intracortical inhibition (ICI), intracortical facilitation (I...

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