Method A 76-year-old woman with the diagnostic suspicion of urinary lithiasis, was subjected to a CT scan with an unknown ICM. Forty-eight hours after the CT scan was carried out, she developed an erythema in both axillae, inframammary folds, cubital and popliteal fossae, such as gluteal and inguinal area, without systemic symptoms. She was treated with methylprednisolone and she began to impro...

BACKGROUND Infection with human herpesvirus 7 (HHV-7) generally results in a febrile illness with accompanying exanthema subitum. OBJECTIVES To ascertain and describe the role of HHV-7 in a case of acute myeloradiculoneuropathy. PATIENT A previously healthy young man with complaints of motor weakness, dysphasia, and nasal voice. METHODS Serological examinations were performed with the pat...

Brazilian spotted fever is an acute febrile infectious disease caused by Rickettsia rickettsii, transmitted by tick bite. As this disease is rare and has high mortality rates in Brazil, the clinical aspects and epidemiological data may help the diagnosis. We report a case of Brazilian spotted fever in a 19-year-old patient who presented maculopapular exanthema in the palmar region and upper lim...

Hyperuricemia is present in approximately 5% of the population, the vast majority of whom are asymptomatic and at no clinical risk. Complications, including renal calculi, uric acid nephropathy and gout, occur in a small proportion of patients. Allopurinol, an analog of hypoxanthine, has been widely used in clinical practice for over 30 years for the treatment of hyperuricemia and gout. Two per...

Interleukin-1R antagonist (anakinra) induces disease remission in about 50% of corticosteroid (CS) resistant cases of systemic onset JIA (SOJIA) [1,2]. Clinicians debate whether etanercept should still be tried first before giving anakinra to such patients. Another, more chalenging, issue is to start anakinra even in CS naïve SOJIA patients. We here report our first experiences of such an appro...

Recent studies have demonstrated a low cross-reactivity between β-lactam antibiotics and carbapenems in IgE-mediated reactions. There are no studies on cross-reactivity of meropenem in patients with non-immediate hypersensitivity to cephalosporins. We describe a case of a 13-year-old male, admitted in Neurosurgery with a severe extradural empyema complicating frontal sinusitis, submitted to an ...