Azar, J. 2014. Automated Tissue Image Analysis Using Pattern Recognition. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology 1175. 106 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9028-7. Automated tissue image analysis aims to develop algorithms for a variety of histological applications. This has important implications in the di...

Objective. To perform linkage analysis between the Short Tandem Repeats (STR) microsatellite markers D19S923, D19S929, D19S22, which are in strong genetic linkage to Notch3 gene in order to contrast the hypothesis that the vascular hereditary dementia phenotype described in a multigenerational extended pedigree from Colombia correspond to CADASIL (Cerebral Autosomal Dominant Arteriopathy with S...

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), is an enduring public health problem globally, particularly in sub-Saharan Africa. Several studies have suggested a role for host genetic susceptibility in increased risk for TB but results across studies have been equivocal. As part of a household contact study of Mtb infection and disease in Kampala, Uganda, we have taken a unique...

8 but only when turning slowly. Molecular motors are not heat engines. If the energy available from the hydrolysis of ATP were uniformly distributed throughout the F 1-ATPase, it would heat up by less than 0.1 ᑻC and then cool off with a decay time of less than 0.1 ns. The energy available from the binding of ATP or the release of inorganic phosphate (or whatever) must be stored in springs (con...

References 1. Macdougall IC, Gray SJ, Elston O, Breen C, Jenkins B, Browne J, et al. Pharmacokinetics of novel erythropoiesis stimulating protein compared with epoetin alfa in dialysis patients. J Am Soc Nephrol 1999;10:2392–5. 2. Sasaki H, Bothner B, Dell A, Fukuda M. Carbohydrate structure of erythropoietin expressed in Chinese hamster ovary cells by a human erythropoietin cDNA. J Biol Chem 1...

Renewal-reward processes are used to provide a framework for the mathematical description of single-molecule bead-motor assays for processive motor proteins. The formulation provides a more powerful, general approach to the fluctuation analysis of bead-motor assays begun by Svoboda et al. (Proc. Natl. Acad. Sci. USA 91(25):11782, 1994). Fluctuation analysis allows one to gain insight into the m...

The human geneticist who wishes to estimate the genetic and environmental components of a quantitative trait has the choice of several sampling designs. Sets of monozygous and dizygous twins, parents and their offspring, and full siblings are often the most convenient samples but invariably yield estimators of genetic variance which are biased by shared environmental factors. More recently, fix...

BACKGROUND Metaplastic carcinoma of the breast is an extremely rare subtype of breast cancer with an incidence of <1% of all breast neoplasms. Metaplastic carcinoma with chondroid differentiation is the rarest among all histologic subtypes of breast cancer. We report a case of infiltrating ductal carcinoma with metaplastic features of chondroid differentiation. CASE PRESENTATION A 58-year-old...

Background Orbital myositis (OM) is an inflammatory condition that mainly involves extraocular muscles. The exact etiology of this disease not known [1]. However, rheumatoid arthritis (RA) has been reported as a possible cause OM in some cases. Objectives aim study was to assess the clinical features and paraclinical data patients with associated RA. Methods This systematic review followed Pref...

In this paper we propose an expanded representation of group belief structures. Three key aspects of belief structures are identified – validity, irrelevance, and uncertainty. Validity arises from the amount of valid beliefs that comprise a group’s belief structure, and the amount of invalid (not corresponding to reality) beliefs in the belief structure. Irrelevance represents the represents th...