BACKGROUND Delayed type hypersensitivity (DTH) response to tuberculin is an important marker of T helper 1 (Th1) mediated acquired immunity against tuberculosis. Depressed DTH responses to tuberculin are observed in immobile elderly individuals with reduced activities of daily living (ADL) scores. Immobility in older people increases the risk of pneumonia related mortality. The decline in the c...

In [C. Benítez, Y. Sarantopoulos, A. Tonge, Lower bounds for norms of products of polynomials, Math. Proc. Cambridge Philos. Soc. 124 (3) (1998) 395–408] it was conjectured that for all unit vectors u1, . . . , ud in Rd , X (u1, . . . , ud ) := sup x∈Rd , |x|2=d d ∏ i=1 〈x,ui〉 1 with equality occurring iff u1, . . . , ud are orthonormal. We relate this to a conjecture about solutions of Ay = y−...

For demonstration of cell-mediated immunity and its role in the process of dermatophytosis, 98 patients with acute dermatophytosis (group I) and 131 chronic dermatophytosis patients (group 2) were chosen. In ail patients, lymphocyte transfonnation and skin test were used. 96 members of group I (98%) had positive delayed-type hypersensitivity (DTH) responses to trichophytin, whereas only 43 ...

Dermatologic TherapyVolume 34, Issue 2 e14941 CORRIGENDUMFree Access Topical treatment for plantar warts: A systematic review This article corrects the following: Sara García-Oreja Francisco Javier Álvaro-Afonso Yolanda García-Álvarez Esther García-Morales Irene Sanz-Corbalán Jose Luis Lázaro Martínez Volume 34Issue 1Dermatologic Therapy First Published online: December 14, 2020 published: 01 A...

The influence of Fe status on cell-mediated immunity was studied in weanling mice fed on Fe-deficient (7 mg Fe/kg), Fe-sufficient (120 mg Fe/kg) and high-Fe (3000 or 5000 mg Fe/kg) diets for 7 weeks. The contact sensitivity (CS) response to dinitrofluorobenzene (DNFB), the in vivo delayed-type hypersensitivity (DTH) response to sheep erythrocytes (SRBC) and the ability of primed spleen cells to...

We have previously demonstrated that suppressor cells can abrogate 4-hydroxy-3nitrophenyl acetyl (NP)l-specific delayed-type hypersensitivity (DTH) responses (13). We now examine the ability of the same population of suppressor cells to abrogate cutaneous sensitivity (CS) responses. Previous studies have noted several differences between the effector T cell populations which mediate DTH and CS ...

Delayed-type hypersensitivity (DTH) appears in mice immunized with less than an optimal immunogenic dose of sheep red blood cells (SRBC), but is blocked progressively as antibody production increases in response to larger doses of SRBC. Treatment with cyclophosphamide (CY) was shown to release T cells from this inhibitory influence of the humoral response, and cause enhancement of DTH. The magn...

We have investigated the effect of orally administered Lactobacillus casei Shirota (L. casei) on immunological memory, as measured by delayed-type hypersensitivity (DTH) and acquired cellular resistance (ACR). The studies were performed in animal models in which the animals were rendered immune by a primary Listeria monocytogenes infection. It was shown that orally administered viable L. casei,...

The intercellular interactions and the site of the genetic defect in delayed-type hypersensitivity (DTH) response to poly(LTyr,LGlu)-poly(DLAla)--poly(LLys) [(T,G)-A--L] has been studied in a system where the T-cell education phase was separated from the efferent phase. In the cellular response, T-T-cell collaboration is required, because T cell-depleted mice were unable to manifest DTH respons...

Cell-mediated immunity plays a crucial role in host defenses against Cryptococcus (Filobasidiella) neoformans. Therefore, the identification of cryptococcal antigens capable of producing T-cell-mediated responses, such as delayed-type hypersensitivity (DTH) reactions, may be useful in the development of immune-based strategies to control cryptococcosis. In order to characterize DTH-producing an...