Hydatid disease is a preventable parasitic disease caused by the Echinococcus, a tapeworm. Even in this 21 st century, it is still not eradicated. Hence, even now we should know about hydatidosis. This review article includes a brief introduction followed by pathology. The various clinical features are discussed in detail. The common complications and some unusual complications are mentioned. A...

The BCVS 2011 Scientific Sessions were held on July 18 to 21, 2011 in New Orleans, Louisiana. The theme of the conference for this year was “From Concept to Clinic: Leading Cardiovascular Translational Science.” The conference gathered 526 attendants, a record number for the BCVS summer conference, from 26 countries. Among them, 280 were either students or early career investigators. There were...

(Molecular Cell 38, 487–499; May 28, 2010) We, the editors of Molecular Cell, were contacted by a concerned reader who informed us about duplicated image that appears in Figure 2A and S1E above paper. These images are pictures untreated control TSC2-/- p53-/- mouse embryonic fibroblasts. The authors no longer have access to original data published 11 years ago, but they believe these likely cam...

RECEPTOR-2 SIGNALING BY DISRUPTING ITS ASSOCIATION WITH CD47* Sukhbir Kaur, Gema Martin-Manso, Michael L. Pendrak, Susan H. Garfield, Jeff S. Isenberg, and David D. Roberts 4 From the Laboratory of Pathology and Laboratory of Experimental Carcinogenesis, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892; Vascular Medicine Institute of the U...

background:diabetic retinopathy (dr) is a sight-threatening microvascular complication of diabetes in which the vascular endothelium is damaged due to oxidative stress and inflammation, and vitreous vegf concentration becomes elevated. the aim of the present study was to assess the association of dr with genetic variations of the mnsod, a major antioxidant enzyme, and vegf, an important mediato...

Mitogen-activated protein kinase (MAPK) signaling pathways are dynamic and sensitive regulators of T cell function and differentiation. Altered MAPK signaling has been associated with the inflammatory and autoimmune diseases lupus and arthritis and with some pathogenic viral infections. HIV-1 infection is characterized by chronic immune inflammation, aberrantly heightened CD8(+) T cell activati...

was described by Harry Platt as the “Mecca of orthopaedics.” The library boasts one of the finest collections of scientific journals and books on orthopaedics, and its shelves are filled with works that have made the history of this discipline. It has often been remembered kindly in the writings of foreign doctors. Besides providing daily help to the medical profession, the library is visited e...

FORSKOLIN-INDUCED CELL SHRINKAGE AND APICAL TRANSLOCATION OF FUNCTIONAL EGFP-HUMAN αENaC IN H441 LUNG EPITHELIAL CELL MONOLAYERS Alison M. Woollhead and Deborah L. Baines Division of Basic Medical Sciences; Ion Channels and Cell Signaling Centre, St. Georges’ University of London, Cranmer Terrace, Tooting, London SW17 0RE, UK. Running title: EGFP-hαENaC expressed in human lung epithelial cells ...

Glucagon-like peptide 1 (GLP-1), produced in the intestine and hindbrain, is known for its glucoregulatory and appetite suppressing effects. GLP-1 agonists are in clinical use for treatment of type 2 diabetes and obesity. GLP-1, however, may also affect brain areas associated with emotionality regulation. Here we aimed to characterize acute and chronic impact of GLP-1 on anxiety and depression-...

GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR REGULATION OF GENES ESSENTIAL FOR SELF-RENEWAL OF MOUSE SPERMATOGONIAL STEM CELLS IS DEPENDENT ON SRC FAMILY KINASE SIGNALING Jon M. Oatley*, Mary R. Avarbock, and Ralph L. Brinster From Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104 USA Running Title: GDNF regulated spermatogonial stem ...