نتایج جستجو برای: donor cornea

تعداد نتایج: 77634  

Journal: :Molecular & cellular proteomics : MCP 2005
Henrik Karring Ida B Thøgersen Gordon K Klintworth Torben Møller-Pedersen Jan J Enghild

Diseases of the cornea are extremely common and cause severe visual impairment worldwide. To explore the basic molecular mechanisms involved in corneal health and disease, the present study characterizes the proteome of the normal human cornea. All proteins were extracted from the central 7-mm region of 12 normal human donor corneas containing all layers: epithelium, Bowman's layer, stroma, Des...

Journal: :Journal of immunology 2009
Holly R Chinnery Eric C Carlson Yan Sun Michelle Lin Sandra H Burnett Victor L Perez Paul G McMenamin Eric Pearlman

The mammalian cornea contains an extensive network of resident macrophages and dendritic cells. To determine the role of these cells in LPS-induced corneal inflammation, TLR4(-/-) mice were sublethally irradiated and reconstituted with bone marrow cells from either enhanced GFP (eGFP)(+)/C57BL/6 or eGFP(+)/TLR4(-/-) mice. The corneal epithelium was abraded, LPS was added topically, and cellular...

2012
Angela N Sheerin S Kaye Smith Katrin Jennert-Burston Amy J Brook Marcus C Allen Badr Ibrahim Dawn Jones Corrin Wallis Katrin Engelmann William Rhys-Williams Richard G A Faragher David Kipling

The human cornea is a tri-laminar structure composed of several cell types with substantial mitotic potential. Age-related changes in the cornea are associated with declining visual acuity and the onset of overt age-related corneal diseases. Corneal transplantation is commonly used to restore vision in patients with damaged or diseased corneas. However, the supply of donor tissue is limited, an...

Journal: :iranian journal of veterinary medicine 2015
foroogh sadat mansoori hamid roshani

background: the ostrich is an interesting subject concerninganimal evolution and morphology studies. it has been speculatedthat ostrich eyes would have distinct tissue structures and this hasnot been previously studied in detail. objectives: the aim of thepresent study was to investigate the histology of the outer layer ofthe ostrich. methods: ten mature ostriches were chosen from anostrich bre...

2015
Gustavo A. Corrales Sina J. Sabet Bhaskar Kallakury Eileen Rusnock Esen K. Akpek

Purpose: To report the ultrastructural and biological features of a gamma-irradiated sterile cornea based on its successful use in a therapeutic penetrating keratoplasty for a case of severe fungal keratitis. Methods: A commercially available acellular, sterile cornea was examined by electron microscopy and immunohistochemical staining after in-vivo explantation in a 50 year-old diabetic male w...

2017
Yang Liu Yingnan Zhang Jing Zhang Jin Yu Qingfeng Liang Zhiqiang Pan

Compared with evident cornea donors (ECDs), deceased potential cornea donors (DPCDs) have no obvious donor identifications to reference, which causes many eligible cornea tissues to be wasted. The demographic characteristics of DPCDs might be different from those of ECDs owing to the following different features: donation consent provided by relatives and willingness to donate before death. Thu...

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