نتایج جستجو برای: developing hippocampus

تعداد نتایج: 389504  

Objective(s): Stress during pregnancy is able to bring extensive effects on neurobehavioral development in offspring. The GABAergic system plays a pivotal role in neuronal excitability, which can be affected by prenatal stress (PS). This study aimed to evaluate impact of the PS on γ2 subunit of gamma-aminobutyric acid A (GABAA) receptor gene expression in the hippocamp...

Journal: :Scholarpedia 2011

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2009
Hervé Fiorentino Nicola Kuczewski Diabe Diabira Nadine Ferrand Menelas N Pangalos Christophe Porcher Jean-Luc Gaiarsa

GABA, the main inhibitory neurotransmitter in the adult brain, has recently emerged as an important signal in network development. Most of the trophic functions of GABA have been attributed to depolarization of the embryonic and neonatal neurons via the activation of ionotropic GABA(A) receptors. Here we demonstrate a novel mechanism by which endogenous GABA selectively regulates the developmen...

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