Drugs with clinical adverse effects are compared in an ex vivo 3-dimensional multi-cellular human liver slice model. Functional markers of oxidative stress and mitochondrial function, glutathione GSH and ATP levels, were affected by acetaminophen (APAP, 1 mM), diclofenac (DCF, 1 mM) and etomoxir (ETM, 100 μM). Drugs targeting mitochondria more than GSH were dantrolene (DTL, 10 μM) and cyclospor...

Dongjie Yin, Pui King Wong, and Tony T. Lee Abstract — A widely adopted two-dimensional Markov chain model of the IEEE 802.11 DCF was introduced by Bianchi to characterize the backoff behavior of a single node under a saturated traffic condition. Using this approach, we propose a queuing model for the 802.11 DCF under a non-saturated traffic environment. The input buffer of each node is modeled...

—In order to evaluate the throughput performance of DCF about both ultra-rate and longtime delay wireless local area network (WLAN) based on Orthogonal Frequency Division Multiplexing (OFDM) modulation channel, this paper analyzes the operating principle of DCF and the throughput of system on the basis of two-dimensional Markov Model. Through theoretical analysis of the relationship among 802....

The purine nucleoside analogues 2-chlorodeoxyadenosine (2-CdA) and 2'-deoxycoformycin (2'-DCF) induce complete remission (CR) in the majority of patients with hairy cell leukemia. However, minimal residual disease (MRD) has been detected in bone marrow core biopsies using immunohistochemical techniques in patients achieving CR by conventional criteria. This study was designed to compare the pre...

Microbial fuel cell (MFC) with a modified anode is one of the new methods to increase MFC efficiency. This study synthesized an cobalt manganese oxide (MnCo2O4@CF) on carbon felt (CF) by easy hydrothermal method and binder-free. Chemical oxygen demand (COD) was measured without diclofenac (DCF). According SEM results, MnCo2O4 uniformly dispersed electrode surface. Moreover, maximum power densit...

Modified phillipsite samples were prepared with two different amounts (monolayer and bilayer coverage) of surfactants octadecyldimethylbenzylammonium chloride (O) dodecylamine (D). Composites characterized by Fourier transform infrared spectroscopy attenuated total reflectance (FTIR–ATR), thermal analysis determination zeta potential, subsequently tested for removal diclofenac sodium (DCF). Dru...

The IEEE 802.11 distributed coordination function (DCF) employs a carrier sensing mechanism, a simple and effective mechanism tomitigate collisions in wireless networks. But the carrier sensing mechanism is inefficient in terms of shared channel use because an overcautious channel assessment approach is used to estimate interference at a receiver. A DCF node simply blocks its transmission when ...

The change of two orders of magnitude in the new DCF of SRE’10, relative to the old DCF evaluation criterion, posed a difficult challenge for participants and evaluator alike. Initially, participants were at a loss as to how to calibrate their systems, while the evaluator underestimated the required number of evaluation trials. After the fact, it is now obvious that both calibration and evaluat...

As a way to value growth opportunities, real options have had a difficult time catching on with managers. Many CFOs believe the method ensures the overvaluation of risky projects. This concern is legitimate, but abandoning real options as a valuation model isn't the solution. Companies that rely solely on discounted cash flow (DCF) analysis underestimate the value of their projects and may fail...