نتایج جستجو برای: crystallins
تعداد نتایج: 1695 فیلتر نتایج به سال:
α-Crystallin is one of the major proteins in the vertebrate eye lens and its function has been indicated to be maintenance of lens transparency. α-Crystallin exists in the lens fiber cell cytoplasm as a polydisperse aggregate with an average molecular mass of approximately 800 kDa. The aggregate is composed of two kinds of polypeptides, αAand αB-crystallins, containing 173 and 175 amino acid re...
alpha-Crystallin has been shown to function as a molecular chaperone in preventing thermal aggregation of crystallins and other proteins. The molecular mechanism of this protection is not yet clear. gamma-Crystallin aggregates upon exposure to UV light. We have investigated the effect of the presence of alpha-crystallin in the photoaggregation process and find that alpha-crystallin does not pre...
The quaternary structure of alpha-crystallin is dynamic, a property which has thwarted crystallographic efforts towards structural characterization. In this study, we have used collision-induced dissociation mass spectrometry to examine the architecture of the polydisperse assemblies of alpha-crystallin. For total alpha-crystallin isolated directly from fetal calf lens using size-based chromato...
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