In mice with a diverse B cell repertoire, hen egg lysozyme (HEL) autoantigen-binding B cells are excluded from follicles and eliminated in 3 days. To explore the roles of competitor B cells and of T cells in this mechanism of self-tolerance, HEL-specific B cells were transferred into mice containing HEL and deficient in endogenous B cells (muMT), T cells (TCR-/-), or B and T cells (RAG1-/-). Pr...

there are a lot of researches in the world about attacks on information systems (is). although there have been many attempts to classify threats of is’s especially in health information systems (his), it is still necessary for all health organization to identify new threats and their sources which threaten security of health care domain. the main aim of this paper is to present a research agend...

Although equilibrium competitive radioligand binding studies are often used to characterize hormone and neurotransmitter receptors, the kinetics of such experiments have not been extensively explored. The interactions of the radioligand and competitor with the receptors can be described by two differential equations which can be solved to yield a single equation describing the binding of the ra...

Businesses routinely rely on econometric models to analyze and predict consumer behavior. Estimation of such models may require combining a firm’s internal data with external datasets to take into account sample selection, missing observations, omitted variables and errors in measurement within the existing data source. In this paper we point out that these data problems can be addressed when e...

Incoming CEOs and general managers don't have much time to show what they can do to improve a business's performance. (In 2006, for instance, about 40% of CEOs who left their jobs had lasted an average of just 1.8 years--and many of them were ushered out the door.) Within a few years at most, leaders must find ways to boost profitability, increase market share, overtake a competitor--whatever t...

With the appearance of multimedia applications and the upcoming age of Voice over IP (VoIP), Voice setup and resources control protocols such as SIP and H.323 over the Internet are becoming increasingly attractive applications. In the last few years as a real competitor in traditional telephony services (PSTN), SIP has gained much attention when compared with H.323. SIP works at presentation an...

Deduplication is a technique used to reduce the amount of storage needed by service providers. It is based on the intuition that several users may want (for different reasons) to store the same content. Hence, storing a single copy of these files would be sufficient. Albeit simple in theory, the implementation of this concept introduces many security risks. In this paper, we address the most se...

Aedes albopictus (Skuse) and Aedes atropalpus (Coquillett) (Diptera: Culicidae) are container-dwelling mosquito species that are well established in the eastern United States. Interspecific larval competition studies have shown Ae. albopictus to be a superior competitor over many species. A laboratory experiment was conducted in artificial containers to evaluate the effects of malathion on larv...

In search advertising, we observe different patterns of branded keyword purchase behavior by the brand owner and its competitor. In particular, under a specific branded keyword, we may observe in the sponsored link, only the brand owner, only the competitor, both, or neither. In this paper, we aim to understand their strategies in a competitive environment. We first derive conditions for each p...

The use of reverse transcription polymerase chain reaction (RT-PCR) with internal RNA competitive standards (competitors) provides a means for measuring absolute amounts of mRNA transcripts in small numbers of cells. Most quantitative competitive (QC)-RT-PCR methods require analysis of multiple reactions to determine the equimolar point of the products produced from mRNA vs. competitor RNA. Her...