This was a preliminary evaluation of 90Y ferric hydroxide colloid for the Radiochemical Centre before using it in patients. Autoradiographs of rabbit knees, both inflamed and non-inflamed, showed that the material was evenly distributed in the synovium, and that there was no evidence of aggregation in vivo. Table I shows the retention of ferric hydroxide colloid in the knees of nine rabbits kil...

Poorly water-soluble drugs frequently solubilize into bile colloids and this natural mechanism is key for efficient bioavailability. We tested the impact of pharmaceutical polymers on solubilization interplay using proton nuclear magnetic resonance spectroscopy, dynamic light scattering, by assessing flux across model membranes. Eudragit E, Soluplus, a therapeutically used polymer, Colesevelam,...

We investigate the assembly of a binary mixture patchy colloids and droplets into crystal structures by use space-filling principle Metropolis Monte Carlo simulations. Here, with six patches in an octahedral symmetry attract droplets, whereas colloid-colloid droplet-droplet pairwise interactions are purely hard-core repulsions. Within parameter space regions that allow for stable crystals, we f...

Background: Hypotension is commonly occurred with Spinal anesthesia. Colloids and Crystalloids are used preoperatively to prevent hypotension. Objective: To examine the effect of fluid (crystalloid vs. colloid) preloading on hemodynamic stability in old patients planned for lower limb orthopedic operations spinal Patients methods: Eighty undergoing surgery under anesthesia were included this wo...

A coarse-graining strategy for dilute and semi-dilute solutions of interacting polymers, and of colloid–polymer mixtures, is briefly described. Monomer degrees of freedom are traced out to derive an effective, state-dependent pair potential between the polymer centres of mass. The cross-over between good and poor solvent conditions is discussed within a scaling analysis. The method is extended ...

A brief review is given on recent studies of charged soft matter solutions, as modelled by the ‘primitive’ approach of strongly coupled Coulomb systems, where the solvent just enters as a dielectric background. These include charged colloids, biological macromolecules such as proteins and DNA, polyelectrolytes and polyelectrolyte stars. Also some original results are presented on colloid–polyel...

The temporal profiles of the emission from titania particle suspensions in Rhodamine 640 perchlorate dye solutions excited by 10-ps pulses of 527-nm radiation were measured over a wide range of particle and dye concentrations and laser powers. The dynamics of stimulated emission from random media is modeled by a random walk of photons within the colloid and rate equations for molecular excitati...

BACKGROUND It has been suspected that synthetic colloids may interfere with leukocyte adhesion by down-regulation of endothelial cell adhesion molecules. Although inhibition of endothelial inflammation might reduce leukocyte-related tissue injury, the same mechanism may be detrimental for host defense during severe infection. Regarding the widespread use of colloids, the authors performed a lab...

UNLABELLED The use of (99m)Tc-sulfur colloid lymphoscintigraphy for the determination of lymph flow patterns from a tumor site and localization of the sentinel node has been widely adopted. However, the effects of multiple injections of the radiopharmaceutical can range from mild discomfort to pain. pH-adjusted lidocaine HCl coadministered with (99m)Tc-sulfur colloid presents a risk of introduc...

We have engineered a class of colloids which can recognize the shape and size of targeted microbial cells and selectively bind to their surfaces. These imprinted colloid particles, whichwe called “colloid antibodies”, were fabricated by partial fragmentation of silica shells obtained by templating the targeted microbial cells. We successfully demonstrated the shape and size recognition between ...