OBJECTIVES Intraindividual cognitive variability (IICV) has been shown to differentiate between groups with normal cognition, mild cognitive impairment (MCI), and dementia. This study examined whether baseline IICV predicted subsequent mild to moderate cognitive impairment in a cognitively normal baseline sample. METHODS Participants with 4 waves of cognitive assessment were drawn from the Wi...

OBJECTIVES To develop the Test Your Memory (TYM)-Spanish version (TYM-S), a self-administered cognitive screening test, in a Chilean older sample and to estimate its psychometric properties and diagnostic accuracy. METHODS The TYM was translated into Spanish and adapted for a Chilean population to develop the TYM-S. Measures of global cognitive impairment and executive dysfunction were admini...

The informant AD8 has good discriminatory indices in detecting questionable dementia. However, studies on participant AD8 yielded inconsistent results. This study aims to investigate the discriminatory ability of the AD8 in detecting cognitive impairment at a memory clinic by comparing the informant AD8, participant AD8, Montreal Cognitive Assessment (MoCA), and Mini-Mental State Examination (M...

The evidence that patients with heart failure (HF) experience cognitive impairment is compelling.1 Cognitive impairment occurs in oneto three-quarters of HF patients2 and leads to poor health outcomes including reduced activities of daily living,3 inadequate engagement in HF self-care,2 clinical instability,4 and premature death.5 The escalating number of research papers investigating cognitive...

Type 2 diabetes mellitus (DM) could be associated with cognitive impairment. The spectrum of cognitive impairment ranges from mild deficits that are not clinically detectable to the most severe clinical form, dementia. Some of the potential mechanisms include the effects of brain infarcts, white matter disease, hyperinsulinaemia, advanced glycosylated end products, and Lipoprotein related prote...

Recent development in molecular imaging enables measurement of fibrillar amyloid plaque in Alzheimer (AD) brain using positron emission tomography (PET). Three tracers (florbetapir, flutemetamol, florbetaben) have been approved by FDA and EMA for use in clinical assessment of memory impairment to exclude AD. The use of amyloid PET imaging is considered to be appropriate in patients with persist...

AIMS/INTRODUCTION The aim of the present research was to study the ghrelin level, executive function and their possible association in patients with type 2 diabetes mellitus. MATERIALS AND METHODS A total of 370 people were recruited between March 2015 and March 2016 in this study. Among them, 212 participants were patients with type 2 diabetes mellitus and 158 participants were included as t...

BACKGROUND Previous research estimates that the majority of athletes with sport-related concussion (SRC) will recover between 7 and 10 days after injury. This short temporal window of recovery is based predominately on symptom resolution and cognitive improvement and does not accurately reflect recent advances in the clinical assessment model. OBJECTIVE To characterize SRC recovery at 1-week ...