PURPOSE To develop and evaluate a software tool for automated detection of focal hyperpigmentary changes (FHC) in eyes with intermediate age-related macular degeneration (AMD). METHODS Color fundus (CFP) and autofluorescence (AF) photographs of 33 eyes with FHC of 28 AMD patients (mean age 71 years) from the prospective longitudinal natural history MODIAMD-study were included. Fully automated...

BACKGROUND New tools are required to improve tuberculosis (TB) diagnosis and treatment, including enhanced ability to compare new treatment strategies. The ELISPOT assay uses Mycobacterium tuberculosis-specific antigens to produce a precise quantitative readout of the immune response to pathogen. We hypothesized that TB patients in The Gambia would have reduced ELISPOT counts after successful t...

This paper presents a traffic-adaptive contention-free period (CFP) extension (TaCFPext) protocol for IEEE 802.15.4 deterministic and synchronous multichannel (DSME) medium access control (MAC), which aims to satisfy the traffic adaptability requirement of industrial wireless sensor networks (IWSNs). The legacy DSME standard has limitations in accommodating highly varying load IWSNs due its fix...

Abstract Lithium‐metal anodes (LMAs) are desirable for next‐generation rechargeable batteries because of their high energy density. However, in practical applications they hindered by inhomogeneous and uncontrolled lithium‐dendrite deposition during cycling. Herein, we propose a dual charge storage mechanism, using freestanding carbon‐fiber paper (CFP) with carbon fillers electrode. These CFP e...

In this research, adsorption experiments were carried out for removal of Basic Blue 41(BB41) dye from an aqueous solution, using coconut fiber particles (CFP) as a low-cost biosorbent. The characteristics of coconut fiber particles weredeterminedwith a scanning electron microscope (FE-SEM) and Fourier Transform Infrared (FTIR) techniques. The effects of initial pH, biosorbentdose, contact time,...

Current methods for fluorescence resonance energy transfer (FRET) microscopy of living cells involve taking a series of images with alternating excitation colors in separate camera exposures. Here we present a new FRET method based on polarization that requires only one camera exposure and thereby offers the possibility for better time resolution of dynamic associations among subcellular compon...

Carbon Flux Phenology (CFP) can affect the interannual variation in Net Ecosystem Exchange (NEE) of carbon between terrestrial ecosystems and the atmosphere. In this study, we proposed a methodology to estimate CFP metrics with satellite-derived Land Surface Phenology (LSP) metrics and climate drivers for 4 biomes (i.e., deciduous broadleaf forest, evergreen needleleaf forest, grasslands and cr...

Epac1 is a guanine nucleotide exchange factor for Rap1 that is activated by direct binding of cAMP. In vitro studies suggest that cAMP relieves the interaction between the regulatory and catalytic domains of Epac. Here, we monitor Epac1 activation in vivo by using a CFP-Epac-YFP fusion construct. When expressed in mammalian cells, CFP-Epac-YFP shows significant fluorescence resonance energy tra...

Frequent itemset mining (FIM) is an essential part of association rules mining. Its application for other data mining tasks has also been recognized. It has been an active research area and a large number of algorithms have been developed. In this paper, we propose another pattern growth algorithm which uses a more compact data structure named Compressed FP-Tree (CFP-Tree). The number of nodes ...