Clinics and pathology Disease NHL of the low to intermediate grade. Phenotype / cell stem origin B-cell lineage. Epidemiology 5% of NHL; sex ratio: 3M/1F; median age: 65 yrs. Clinics Advanced disease (Ann Harbor stage III-IV) with generalized lymphadenopathies in 90%, bone marrow involvement (70%), frequent splenomegaly (50%), hepatomegaly (30%), and gastro-intestinal involvement (20%), and lym...

Sickle cell disease (SCD) is an inherited blood disorder that affects red cells. The study was conducted in Elobied town during the period May 2011 to September 2011. aim of this detect abnormalities leucocytes among sickle anemic patients. 40 patients; age range between 8 months 23 years. Blood sample taken for all patients and laboratory investigation were performed using automated estimation...

BACKGROUND Information on the prognostic utility of the admission complete blood count (CBC) and differential count is lacking. OBJECTIVE To identify independent predictors of mortality from the varied number and morphology of cells in the complete blood count defined as a hemogram, automated five cell differential count and manual differential count. DESIGN Retrospective cohort study and c...

Abstract Familial hemophagocytic lymphohistiocytosis (FHL) is a genetically heterogeneous disorder which less typical in adults than pediatric patients. In this study, we reported rare case of adult-onset FHL3 with progressive lymphocytosis and lymphocytic interstitial pneumonia (LIP). A 20-year old female was admitted to our institution for persistent cough fever. chest high-resolution compute...

In the last years several borderline B-cell lymphoid proliferations have been recognized that lie at interface between benign and malignant. These lesions can be divided in two groups; those considered precursor of well malignancies group indolent lymphomas with limited potential for progression. Precursor are monoclonal share many genetic features their malignant counterpart. The first lesion ...

Acute Epstein-Barr virus (EBV) infection results in an unusually robust CD8(+) T cell response in young adults. Based on mouse studies, such a response would be predicted to result in attrition of preexisting memory to heterologous infections like influenza A (Flu) and cytomegalovirus (CMV). Furthermore, many studies have attempted to define the lymphocytosis that occurs during acute EBV infect...