segmental defects of the tibia are challenging therapeutic problems for both the physician and the patient. these defects may be caused by severe trauma, infection, tumors and congenital processes. several different techniques have been described for treatment of these defects including the papineau technique, allograft reconstruction, bone transport using the ilizarov frame, free vascularized ...

The current strategies for healing bone defects are numerous and varied. At the core of each bone healing therapy is a biomimetic mechanism, which works to enhance bone growth. These range from porous scaffolds, bone mineral usage, collagen, and glycosaminoglycan substitutes to transplanted cell populations. Bone defects face a range of difficulty in their healing, given the composite of dense ...

Watkins, Lauren E. M.S.B.M.E., Purdue University, May 2016. Densified Collagen-Fibril Biomaterials for Bone Tissue Engineering. Major Professor: Sherry Voytik-Harbin. Millions of craniofacial bone defects occur annually as a result of trauma, congenital defects, disease, or tooth extraction1, 2. When present in the oral cavity, these defects are associated with adverse impacts on speech, mastic...

Biomineralization Article 2200976 by Luiz E. Bertassoni and co-workers presents injectable cell-laden bone-like tissue constructs that show promise as minimally invasive growth factor-free alternatives to bone autografts for repair regeneration of critical sized defects. By approximating the cellular, structural, chemical composition native bone, engineered microconstructs promote native-like m...

holt-oram syndrome is an autosomal dominant disorder, characterised by skeletal abnormalities of the upper limb associated with congenital heart defect, mainly atrial and ventricular septal defects. skeletal defects exclusively affect the upper limbs in the preaxial radial ray distribution and are bilateral and asymmetrical. they range from clinodactyly, absent or digitalised thumb, hypoplastic...

J Bone Joint Surg [Br] 2009;91-B:271-7. Received 16 June 2008; Accepted after revision 26 September 2008 The treatment of bony defects of the tibia at the time of revision total knee replacement is controversial. The place of compacted morsellised bone graft is becoming established, particularly in contained defects. It has previously been shown that the initial stability of impaction-grafted t...

BACKGROUND The guided bone regeneration (GBR) technique is highly successful for the treatment of peri-implant bone defects. The aim was to determine whether or not implants associated with GBR due to peri-implant defects show the same survival and success rates as implants placed in native bone without defects. MATERIAL AND METHODS Patients with a minimum of two submerged dental implants: on...

In this review, we explore the application of novel biomaterial-based therapies specifically targeted towards craniofacial bone defects. The repair and regeneration critical sized defects in region requires use bioactive materials to stabilize expedite healing process. However, existing clinical approaches face challenges effectively treating complex defects, including issues such as oxidative ...

statement of problem: digital measurement of rvg may improve diagnostic interpretation of radiographs in terms of accuracy, although it has been shown that validity of linear measurements of interproximal bone loss could not be improved by basic digital manipulations. purpose: the aim of this study was to evaluate the accuracy of radiovisiography (rvg) in the linear measurement of interproximal...