First examples of multichain (polycatenar) compounds, based on the π-conjugated [1]benzothieno[3,2-b]benzothiophene unit are designed, synthesized, and their soft self-assembly charge carrier mobility investigated. These terminated by new fan-shaped 2-brominated 3,4,5-trialkoxybenzoate moiety, form bicontinuous cubic liquid crystalline (LC) phases with helical network structure over extremely w...

The clinical benzothiophene SERM (BT-SERM), raloxifene, was compared with estrogens in protection of primary rat neurons against oxygen-glucose deprivation (OGD). Structure-activity relationships for neuroprotection were determined for a family of BT-SERMs displaying a spectrum of ERα and ERβ binding affinity and agonist/antagonist activity, leading to discovery of a neuroprotective pharmacopho...

We report on the synthesis of a novel class functionalized thia[6]helicenes and thia[5]helicene, containing benzothiophene unit second heteroatom embedded in helix (i.e., nitrogen oxygen) or pyrene spirobifluorene moiety. These systems are obtained through straightforward general procedures that involve: (i) palladium-catalyzed annulation iodo-atropoisomers with internal alkynes (ii) Suzuki cou...

[1]Benzothieno[3,2-b]benzothiophene (BTBT) derivatives are widely employed as hole transport materials in organic field-effect transistors. The electronic properties of these depend critically on the crystal packing, which turn depends choice attached functional group. With symmetrically alcohol chains, structure may display different packing modes depending number CH2 groups alkyl chain. dipen...