an attempt to see when these properties attain their normal values during the course of treatment of kala-azar patients, it was found that even after a period of two months after the courses of injections are finished, the serum does not attain its normal value so far as these physical properties are concerned. Simultaneously with these experiments, Napier's aldehyde reaction has also been foll...

Bihar, India has been in the grip of kala-azar for many years. Its rampant and severe spread has made life miserable in most parts of the state. Such conditions require a comprehensive understanding of this affliction. The numbers coming out of the districts prone to the disease in the north and south Ganges have provided us with several startling revelations, as there are striking uniformities...

mammalian hosts (9). Drug resistance or sensitivity is based on sequences of M2 and NA. Substitution within residues including L26I, V27A/I, A30S, and S31N of the M2 ion channel protein was used to predict amantadine-resistant mutants, and H274Y of the NA was used to predict for oseltamivir resistance (10). The virus observed in 2006 isolates from Phichit was resistant to amantadine but sensiti...

leishmaniasis is an endemic parasitic disease in iran. this paper reports the case of a 5-yr-old boy who presented with multiple isolated cervical lymphadenopathy for several months with no history of fever and no signs or symptoms. in an excisional lymph node biopsy, leishmania parasites were histologically detected. thus, leishmaniasis should be included in the differential diagnosis of isola...

It is suggested that previous data indicate 3 major epidemics of kala-azar in Assam between 1875 and 1950, with inter-epidemic periods of 30-45 and 20 years. This deviates from the popular view of regular cycles with a 10-20 year period. A deterministic mathematical model of kala-azar is used to find the simplest explanation for the timing of the 3 epidemics, paying particular attention to the ...

Objectives: A rapid immunochromatographic dipstick test (ICT) has become available for the qualitative detection of anti-Leishmania antibody using recombinant rK39 antigen. This study was carried out at the department of Microbiology of Rajshahi Medical College, Bangladesh, in order to evaluate the diagnostic potential of immunochromatographic dipstick test. Methodology: A total of one hundred ...

Using a randomized study, we compared a daily and an alternate-day regimen of amphotericin B for the treatment of kala-azar, with respect to efficacy, adverse reactions, cost-effectiveness, and tolerance. The study subjects were 80 kala-azar patients, drawn from the first four decades of life and matched by age, sex, and parasite load. The patients were randomly allocated to treatment groups A ...