نتایج جستجو برای: adrenal insufficiency
تعداد نتایج: 151338 فیلتر نتایج به سال:
Adrenal insufficiency is managed by hormone replacement therapy, which is far from optimal; the ability to generate functional steroidogenic cells would offer a unique opportunity for a curative approach to restoring the complex feedback regulation of the hypothalamic-pituitary-adrenal axis. Here, we generated human induced steroidogenic cells (hiSCs) from fibroblasts, blood-, and urine-derived...
Rifampicin is a potent inducer of hepatic microsomal enzymes and increases the oxidation of cortisol to 63-hydroxycortisol.2 As the major pathway of cortisol metabolism involving tetrahydroreduction of the A ring is not thought to be altered this increased utilisation usually represents only a small percentage of the cortisol produced in patients with normal adrenal function. In patients with p...
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