نتایج جستجو برای: adaptors
تعداد نتایج: 1508 فیلتر نتایج به سال:
Shc (Src homology and collagen homology) proteins are considered prototypical signalling adaptors in mammalian cells. Consisting of four unique members, ShcA, B, C and D, and multiple splice isoforms, the family is represented in nearly every cell type in the body, where it engages in an array of fundamental processes to transduce environmental stimuli. Two decades of investigation have begun t...
Cul3, a Cullin family scaffold protein, is thought to mediate the assembly of a large number of SCF (Skp1-Cullin1-F-box protein)-like ubiquitin ligase complexes through BTB domain substrate-recruiting adaptors. Cul3 controls early embryonic development in several genetic models through mechanisms not understood. Very few functional substrate/adaptor pairs for Cul3 ubiquitin ligases have been id...
Open Educational Resources (OER) are reducing barriers to education while allowing creators the opportunity share their work with world and continue owning copyright of work. To support new authors adaptors in OER space, we provide an overview common considerations that should make respect issues related context OER. Further, importantly, a challenge space is ensuring original receive appropria...
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