In recent years, there has been considerable research in preparing materials and finding new uses for nanoscale structures in drug delivery. Uses such as carriers for controlled and targeted drug delivery, micropatterned devices, systems for biological recognition, have shown the versatility of these biopolymeric materials [1]. We report on major new developments of recognitive drug delivery sy...

Carbonitriles and alcohols react in a Lewis acid-promoted Pinner reaction to carboxylic esters. Best results are obtained with two equivalents of trimethylsilyl triflate as Lewis acid. Good yields are achieved with primary alcohols and aliphatic or benzylic carbonitriles, but the straightforward synthesis of acrylates and benzoates starting with acrylonitrile and benzonitrile, respectively, is ...