A majority of the Indian dogs are ‘community dogs’, semiferal dogs which are partially dependent on the human population and feral dogs. Communicable diseases may be a problem due to overcrowding, minimal veterinary care, and a climate favouring parasites and vectors. Some reports suggest that the vectorborne diseases, such as filariosis, babesosis and ehrlichiosis, are endemic throughout India...

Covering two-thirds of our planet, the global deep ocean plays a central role in supporting life on Earth. Among other processes, this biggest ecosystem buffers the rise of atmospheric CO2. Despite carbon sequestration in the deep ocean has been known for a long time, microbial activity in the meso- and bathypelagic realm via the "assimilation of bicarbonate in the dark" (ABD) has only recently...

Lantibiotics are ribosomally synthesized and post-translationally modified peptide antibiotics that contain unusual amino acids such as dehydro and lanthionine residues. Nukacin ISK-1 is a class II lantibiotic, whose precursor peptide (NukA) is modified by NukM to form modified NukA. ATP-binding cassette (ABC) transporter NukT is predicted to cleave off the N-terminal leader peptide of modified...

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LuxR solo transcriptional regulators contain both an autoinducer binding domain (ABD; N-terminal) and a DNA binding Helix-Turn-Helix domain (HTH; C-terminal), but are not associated with a cognate N-acyl homoserine lactone (AHL) synthase coding gene in the same genome. Although a few LuxR solos have been characterized, their distributions as well as their role in bacterial signal perception and...

1 tation of filamin B at the actin-binding domain. 2 3 Yongtong Zhao, Sandor S. Shapiro† and Masumi Eto 4 5 Department of Molecular Physiology and Biophysics, Sidney Kimmel Medical College at Thomas Jef6 ferson University, and Sidney Kimmel Cancer Center, 1020 Locust Street, 436 Jefferson Alumni Hall, 7 Philadelphia, Pennsylvania 19107, USA 8 9 Running Head: Human filamin B mutations in cell dy...

The purpose of this study was to identify the spatiotemporal determinants of the cough motor pattern. We speculated that the spatial and temporal characteristics of the cough motor pattern would be regulated separately. Electromyograms (EMG) of abdominal muscles (ABD, rectus abdominis or transversus abdominis), and parasternal muscles (PS) were recorded in anesthetized cats. Repetitive coughing...

Crustaceans possess a diverse array of specialized limbs. Although shifts in Hox gene expression domains have been postulated to play a role in generating this limb diversity, little functional data have been provided to understand the precise roles of Hox genes during crustacean development. We used a combination of CRISPR/Cas9-targeted mutagenesis and RNAi knockdown to decipher the function o...