نتایج جستجو برای: a a614t gene
تعداد نتایج: 13657393 فیلتر نتایج به سال:
the androgen insensitivity syndrome is a heterogeneous disorder with a wide spectrum of phenotypic abnormalities, ranging from complete female to ambiguous forms that more closely resemble males. the primary abnormality is a defective androgen receptor protein due to a mutation of the androgen receptor gene. this prevents normal androgen action and thus leads to impaired virilization. a point m...
Bovine chymosin enzyme is one of the most commonly used enzymes in the dairy industry. The production of this enzyme from its natural source does not meet the needs of this huge industry. The production of recombinant bovine chymosin in plants can be a good alternative to native enzyme. Insertion and expression of foreign genes in plants can occur in the nucleus and chloroplast organelles. The ...
Background and Objective: Myocardial infraction can lead to loss of heart muscle cell, changes in ventricular function and structure, scar formation as well as leading the heart to ultimate stroke and its loss. This[J1] study aimed to investigate the effect of eight weeks of High-Intensity Interval Training (HIIT) on the gene expression of angiogenesis factors in ischemic rats. Materials and ...
objective: survey of molecular characterization of nucleoprotein gene of h9n2 avian influenza viruses and determination of the genetic relationship of iranian h9n2 viruses and other asian viruses. materials and methods: the nucleoprotein (np) genes from 4 isolates of h9n2 viruses isolated from commercial chickens in iran during 2008-2009 were amplified by rt-pcr method and sequenced. nucleotid...
Background: The molecular studies indicate some of the genes in the promoter region itself, will undergo methylation. Methylation of CpG islands in the promoter region of that cause silence or reduced expression of genes involved in cell growth pathways, which are colorectal cancer causing agents. Detection of methylation status can be used as a marker for cancer diagnosis and prediction of dis...
background: the double heterozygous state of α/β thalassemia may alter the hematological indices and modify the phonotype. in addion, definite characterizaon of co-inheritance of α- and β-thalassemia heterozygous carriers may change the process of genec counseling. materials and methods: an iranian couple with low hematological indices was analyzed for α-globin gene deleons using mulplex g...
Eggshell quality is the main trait to assess egg quality. Marker assisted selection can be used to improve this trait. During eggshell formation, a mass of inorganic minerals is deposited. The Sodium Channel (SCNN1) gene family plays an essential role in cation transportation and SCNN1g is a member of this gene family. The objective of this study was to estimate the frequency of SCNN1g gene var...
Background and purpose: Toxoplasmosis is a common parasitic disease throughout the world and one-third of the population has antibodies to Toxoplasma gondii. This disease causes serious medical problems in fetuses and immunocompromised individuals. As gene encoding protein GRA14 can be considered as a suitable target for DNA vaccine and designing diagnostic kits the aim of this study was to ...
Background and Objective: The severity of the spinal muscular atrophy phenotype is inversely associated with the expression levels of the SMN2 gene; this correlation is not absolute, for this reason there is currently no effective treatment. The interference of other severity modifying factors, apart from SMN2 gene expression has been suggested. Here we investigate the effects of valproic acid ...
Introduction: Systemic lupus erythematosus (SLE) is a chronic systemic inflammatory autoimmune disease characterized by a breakdown of self-tolerance. Transforming growth factor-β1 is a cytokine produced by both immune and non immune cells, and it has a wide operating range. human TGF-β1 gene is located on chromosome 19q13 . The aim of this study was investigating the TGF-β1 Gene...
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