The mutagenicity of six heterocylic nitrogen mustards (ICR compounds) has been determined in a cultured mammalian cell system by use of resistance to the purine analog 6-thioguanine to select for mutation induction at the hypoxanthine-guanine phosphoribosyltransferase locus in Chinese hamster ovary cells. The six compounds tested are ICR 191, 170, 292, 372, 191-OH, and 170-OH. The first four co...

be a distinct class of accessory factors, which we term " plus-end-tracking proteins " or ϩTIPs. These MAPs are among the most conserved components of the MT cy-toskeleton. They localize to the MT plus end, and in living cells, they mark growing plus ends and thus give The Children's Hospital the appearance of " tracking. " Recently, studies from a Harvard Medical School variety of organisms ha...

Thermal formation of free radicals in flumetasone sterilized according to the pharmaceutical norms at 160, 170 and 180 °C was examined by electron paramagnetic resonance (EPR) spectroscopy. The microbiological analysis was done. Similar free radical concentrations were measured for flumetasone sterilized at 160 and 170 °C. The concentration was considerably higher than that for flumetasone ster...

We review how to obtain the thermodynamic Bethe Ansatz (TBA) equations for the antiferromagnetic Heisenberg ring in an external magnetic field. We review how to solve these equations for low temperature and small field, and calculate the specific heat and magnetic susceptibility. 1. Motivation Quantum spin chains provide some of the simplest examples of physical systems with quantum-algebra sym...

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Dobrek Ł. Oxidative stress mechanisms as potential therapeutic targets in chronic kidney disease. Medical Studies/Studia Medyczne. 2022;38(2):163-170. doi:10.5114/ms.2022.117714. APA Dobrek, (2022). Medyczne, 38(2), 163-170. https://doi.org/10.5114/ms.2022.117714 Chicago Łukasz. 2022. "Oxidative disease". Medyczne...

High-resolution solid state nTo NMR spectra of nTo-enficbed compounds were observed with multiple-quantum magic-angle-spinning (MQMAS) experiments. The resolution of the 170 MQMAS spectra is approximately 30to 150-fold higher than that found in conventional 170 MAS spectra, making it possible to detect crystallographically distinct oxygen sites. It is shown that into MQMAS studies are feasible ...