This ancient institution (one of the first, if not the oldest, asylums for lunatics in Europe) was founded in 1247, during the reign of Henry III., by Simon Fitzmary, a sheriff of London, at Bishopsgate, when it was designated the Priory of Bethlehem, At the dissolution of the religious houses, the property was seized by Henry VIII., who in 1547 granted the Priory, with all its revenues, to the...

OBJECTIVE To assess hypertension control in patients admitted to hospital for an acute coronary event and to investigate the influence on prognosis of controlling hypertension before hospital discharge. DESIGN Multicentre retrospective cohort study. METHODS The medical records were examined of all patients admitted in 77 cardiological centres on January 1998 for myocardial infarction or uns...

This study aimed to investigate the potential misuse of novel oral anticoagulants (NOACs) and the physicians' adherence to current European guideline recommendations in real-world using a large dataset from Real-life Multicenter Survey Evaluating Stroke Prevention Strategies in Turkey (RAMSES Study).RAMSES study is a prospective, multicenter, nationwide registry (ClinicalTrials.gov identifier N...

Thorne, H. V. (University of Minnesota, Minneapolis). Electrophoretic study of the interaction of radioactive poliovirus with components of cultured cells. J. Bacteriol. 85:1247-1255. 1963.-The interaction of P(32)-labeled poliovirus with the postnuclear fraction of HeLa cell homogenates was first examined using radioactivity to quantitate the reaction. The effects of virus and debris concentra...

Mutations in domain II of Escherichia coli 23 S rRNA that cause resistance to erythromycin do so in a manner fundamentally different from mutations at the drug binding site in domain V of the 23 S rRNA. The domain II mutations are located in a hairpin structure between nucleotides 1198 and 1247. This is close to a short open reading frame in the 23 S rRNA that encodes a pentapeptide (E-peptide)...

BACKGROUND The pattern of neurological admissions varies amongst different regions of the world and this depends on many factors including the regional burden of neurological disorders. This study determined the pattern of neurological admissions in a tertiary health centre in Abakaliki South Eastern Nigeria and compared it with that from other parts of the country. METHODOLOGY A review of ad...

Testing for (1→3)-beta-D-glucan (BDG) is used for detection of invasive fungal infection. However, current assays lack automation and the ability to conduct rapid single-sample testing. The Fungitell assay was adopted for automation and evaluated using clinical samples from patients with culture-proven candidemia and from culture-negative controls in duplicate. A comparison with the standard as...

147 Rev Esp Cardiol. 2005;58(10):1246-8 1247 ment by those who defend the two-stage procedures was not especially notable in our case. Circulatory arrest with deep hypothermia avoids subjecting the liver and kidneys to periods of warm ischemia. Other advantages of this technique are the physical benefits for the patient and economic benefits for the system, as the surgery is performed in a sing...

cerebellar degeneration 3 4 Ritsuko Hanajima, Reza Shadmehr, Shinya Ohminami, Ryosuke Tsutsumi, Yuichiro Shirota, Takahiro 5 Shimizu, Nobuyuki Tanaka, Yasuo Terao, Shoji Tsuji, Yoshikazu Ugawa, Motoaki Uchimura, 6 Masato Inoue, Shigeru Kitazawa 7 8 1. Department of Neurology, University of Tokyo Hospital, Tokyo, Japan 113-8655 9 2. Division of Neuroscience, Graduate School of Medicine, the Univ...

AIMS Although acute venous thrombo-embolism (VTE) often afflicts patients with advanced age, the predictors of in-hospital mortality for elderly VTE patients are unknown. METHODS AND RESULTS Among 1247 consecutive patients with acute VTE from the prospective SWIss Venous ThromboEmbolism Registry (SWIVTER), 644 (52%) were elderly (≥65 years of age). In comparison to younger patients, the elder...