An objective noninvasive biomarker for fruit and vegetable (FV) consumption would help to more reliably characterize the relationship between FV intake and health status in observational studies. Because increases in urinary hippuric acid (HA) were observed after consumption of several FV varieties, we aimed to investigate whether 24-h urinary HAmay represent a potential biomarker for FV consum...

SCOPE Aim of this study was to investigate urinary excretion and metabolism of procyanidins a group of secondary plant metabolites with many beneficial health effects described in literature. METHODS AND RESULTS To investigate the metabolism of procyanidins in the absence of flavan-3-ols, centrifugal partition chromatography was used for their reduction in a grape seed extract to a level of a...

MANDELIc acid, when administered to animals, may be recovered almost quantitatively from the urine. Moreover, when mandelic acid appears in the body as the result of metabolic processes, it is supposed to be excreted without further change [Knoop, 1905; Dakin, 1922; Quick, 1928]. Neubauer [1909], Neubauer & Fischer [1910], Neubauer & Gross [1910] and Neubauer & Warburg [1910] claimed that after...

Proteus mirabilis, a common agent of nosocomially acquired and catheter-associated urinary tract infection, is the most frequent cause of infection-induced bladder and kidney stones. Urease-catalyzed urea hydrolysis initiates stone formation in urine and can be inhibited by acetohydroxamic acid and other structural analogs of urea. Since P. mirabilis urease is inducible with urea, there has bee...