the vehicle driving comfort has become one of the important factors of vehicle quality and receives increasing attention. in this paper, optimal points of vehicle suspension parameters are generated using modified non-dominated sorting genetic algorithm (nsga-ii) for pareto optimization of 5-degree of freedom vehicle vibration model considering three conflicting functions simultaneously. in thi...

in our country, student transportations’ security and driving accidents statistics for students is one of the major concerns for relevant organizations such as educational organization. in current year, a system, was named sepand, was formed in city taxi driver :::::::union::::::: by educational organization, naja traffic and city taxi driver :::::::union:::::::. in this systems’ plan, basis on...

Vehicle Routing Problem (VRP) is addressed to a class of problems for determining a set of vehicle routes, in which each vehicle departs from a given depot, serves a given set of customers, and returns back to the same depot. On the other hand, simultaneous delivery and pickup problems have drawn much attention in the past few years due to its high usage in real world cases. This study, therefo...

Dopamine transporter deficiency syndrome due to SLC6A3 mutations is the first inherited dopamine 'transportopathy' to be described, with a classical presentation of early infantile-onset progressive parkinsonism dystonia. In this study we have identified a new cohort of patients with dopamine transporter deficiency syndrome, including, most significantly, atypical presentation later in childhoo...

Creatine, a compound that is critical for energy metabolism of nervous cells, crosses the blood-brain barrier (BBB) and the neuronal plasma membrane with difficulty, and only using its specific transporter. In the hereditary condition where the creatine transporter is defective (creatine transporter deficiency) there is no creatine in the brain, and administration of creatine is useless lacking...

tehran is located in a valley at the foot of the alborz mountains in northern iran (35 degrees latitude north). urban expansion in tehran resulted from a high rate of population growth and rural-urban migration combined with a strong tradition of centralization in the capital. airborne particulate of tehran's atmosphere was fractionated in a 6-stage high-volume cascade impactor. the first ...

objectives: one of the applications of ergonomics disciplinary is designing driver workstation compatible to users’ characteristics. the aim of this study was evaluation of interior design of shoka vehicle with respect to the accommodation for iranian population and proposing suggestions for customizing design of the vehicle. methods: this study was a descriptive-analytical study conducted amon...

Patients undergoing continuous ambulatory peritoneal dialysis are classified according to their peritoneal permeability as low transporter (low solute permeability) or High transporter (high solute permeability). Factors that determine the differences in permeability between them have not been fully disclosed. We investigated morphological features of cultured human peritoneal mesothelial cells...

Complementary DNA encoding a facilitative glucose transporter was isolated from a human hepatoma cell line (HepG2) cDNA library and subcloned into a metal-inducible mammalian expression vector, pLEN (California Biotechnology) containing human metallothionein gene II promoter sequences. Chinese hamster ovary (CHO) cells transfected with this transporter expression vector, pLENGT, exhibited a 2-1...

Abstract Glutamine transporters transport different amino acids for cell growth and metabolism. In tumor cells, glutamine are often highly expressed play a crucial role in their growth. By inhibiting the acid of these transporters, cancer cells can be inhibited. recent years, more attention has been paid to study transporter. this article, differences between ASC system transporter 2 (ASCT2), L...